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Disease

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Disease Compass- a navigation system for disease knowledge based on ontology and linked data techniques.

Journal of biomedical semantics
BACKGROUND: Medical ontologies are expected to contribute to the effective use of medical information resources that store considerable amount of data. In this study, we focused on disease ontology because the complicated mechanisms of diseases are r...

A disease similarity matrix based on the uniqueness of shared genes.

BMC medical genomics
BACKGROUND: Complex diseases involve many genes, and these genes are often associated with several different illnesses. Disease similarity measurement can be based on shared genotype or phenotype. Quantifying relationships between genes can reveal pr...

Network mirroring for drug repositioning.

BMC medical informatics and decision making
BACKGROUND: Although drug discoveries can provide meaningful insights and significant enhancements in pharmaceutical field, the longevity and cost that it takes can be extensive where the success rate is low. In order to circumvent the problem, there...

Using classification models for the generation of disease-specific medications from biomedical literature and clinical data repository.

Journal of biomedical informatics
OBJECTIVE: Mining disease-specific associations from existing knowledge resources can be useful for building disease-specific ontologies and supporting knowledge-based applications. Many association mining techniques have been exploited. However, the...

Evaluating the effect of annotation size on measures of semantic similarity.

Journal of biomedical semantics
BACKGROUND: Ontologies are widely used as metadata in biological and biomedical datasets. Measures of semantic similarity utilize ontologies to determine how similar two entities annotated with classes from ontologies are, and semantic similarity is ...

Disorder recognition in clinical texts using multi-label structured SVM.

BMC bioinformatics
BACKGROUND: Information extraction in clinical texts enables medical workers to find out problems of patients faster as well as makes intelligent diagnosis possible in the future. There has been a lot of work about disorder mention recognition in cli...

Disease named entity recognition by combining conditional random fields and bidirectional recurrent neural networks.

Database : the journal of biological databases and curation
The recognition of disease and chemical named entities in scientific articles is a very important subtask in information extraction in the biomedical domain. Due to the diversity and complexity of disease names, the recognition of named entities of d...

Dione: An OWL representation of ICD-10-CM for classifying patients' diseases.

Journal of biomedical semantics
BACKGROUND: Systematized Nomenclature of Medicine - Clinical Terms (SNOMED CT) has been designed as standard clinical terminology for annotating Electronic Health Records (EHRs). EHRs textual information is used to classify patients' diseases into an...

Semi-supervised learning of the electronic health record for phenotype stratification.

Journal of biomedical informatics
Patient interactions with health care providers result in entries to electronic health records (EHRs). EHRs were built for clinical and billing purposes but contain many data points about an individual. Mining these records provides opportunities to ...

Text mining electronic hospital records to automatically classify admissions against disease: Measuring the impact of linking data sources.

Journal of biomedical informatics
OBJECTIVE: Text and data mining play an important role in obtaining insights from Health and Hospital Information Systems. This paper presents a text mining system for detecting admissions marked as positive for several diseases: Lung Cancer, Breast ...