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DNA Topoisomerases, Type II

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Differential gene expression analysis and machine learning identified structural, TFs, cytokine and glycoproteins, including SOX2, TOP2A, SPP1, COL1A1, and TIMP1 as potential drivers of lung cancer.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 39888730
BACKGROUND: Lung cancer is a primary global health concern, responsible for a considerable portion of cancer-related fatalities worldwide. Understanding its molecular complexities is crucial for identifying potential targets for treatment. The goal i...
Biomarkers, Tumor Collagen Type I Collagen Type I, alpha 1 Chain DNA Topoisomerases, Type II Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks Humans Lung Neoplasms Machine Learning Osteopontin Poly-ADP-Ribose Binding Proteins Protein Interaction Maps SOXB1 Transcription Factors Tissue Inhibitor of Metalloproteinase-1
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