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Poly-ADP-Ribose Binding Proteins

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Machine learning-based prediction of microsatellite instability and high tumor mutation burden from contrast-enhanced computed tomography in endometrial cancers.

Scientific reports 33082371
To evaluate whether radiomic features from contrast-enhanced computed tomography (CE-CT) can identify DNA mismatch repair deficient (MMR-D) and/or tumor mutational burden-high (TMB-H) endometrial cancers (ECs). Patients who underwent targeted massive...
Aged Carcinoma, Endometrioid Cohort Studies Computer Simulation DNA Mismatch Repair DNA Polymerase II Endometrial Neoplasms Female Humans Machine Learning Microsatellite Instability Middle Aged Mutation Neoplasm Staging Poly-ADP-Ribose Binding Proteins Prognosis Tomography, X-Ray Computed Tumor Suppressor Protein p53 Uterus
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Deep learning based analysis of G3BP1 protein expression to predict the prognosis of nasopharyngeal carcinoma.

PloS one 39869565
BACKGROUND: Ras-GTPase-activating protein (GAP)-binding protein 1 (G3BP1) emerges as a pivotal oncogenic gene across various malignancies, notably including nasopharyngeal carcinoma (NPC). The use of automated image analysis tools for immunohistochem...
Adult Biomarkers, Tumor Deep Learning DNA Helicases Female Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Male Middle Aged Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms Poly-ADP-Ribose Binding Proteins Prognosis RNA Helicases RNA Recognition Motif Proteins
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Differential gene expression analysis and machine learning identified structural, TFs, cytokine and glycoproteins, including SOX2, TOP2A, SPP1, COL1A1, and TIMP1 as potential drivers of lung cancer.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 39888730
BACKGROUND: Lung cancer is a primary global health concern, responsible for a considerable portion of cancer-related fatalities worldwide. Understanding its molecular complexities is crucial for identifying potential targets for treatment. The goal i...
Biomarkers, Tumor Collagen Type I Collagen Type I, alpha 1 Chain DNA Topoisomerases, Type II Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks Humans Lung Neoplasms Machine Learning Osteopontin Poly-ADP-Ribose Binding Proteins Protein Interaction Maps SOXB1 Transcription Factors Tissue Inhibitor of Metalloproteinase-1
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