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Collagen Type I, alpha 1 Chain

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Mechanisms of QingRe HuoXue Formula in atherosclerosis Treatment: An integrated approach using Bioinformatics, Machine Learning, and experimental validation.

International immunopharmacology 39137627
BACKGROUND: Atherosclerosis (AS) is the main cause of coronary heart disease, cerebral infarction, and peripheral vascular disease. QingRe HuoXue Formula (QRHXF), a common prescription of traditional Chinese medicine, has a definite effect on the cli...
Animals Atherosclerosis Collagen Type I Collagen Type I, alpha 1 Chain Computational Biology Disease Models, Animal Drugs, Chinese Herbal Gene Expression Profiling Humans Machine Learning Male Mice Mice, Inbred C57BL Molecular Docking Simulation Plaque, Atherosclerotic
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The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis.

Biology direct 39780278
BACKGROUND: Endothelial cells are integral components of the tumor microenvironment and play a multifaceted role in tumor immunotherapy. Targeting endothelial cells and related signaling pathways can improve the effectiveness of immunotherapy by norm...
Collagen Type I Collagen Type I, alpha 1 Chain Endothelial Cells Humans Immunotherapy Machine Learning Male Prognosis Prostatic Neoplasms Single-Cell Analysis Tumor Microenvironment
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Differential gene expression analysis and machine learning identified structural, TFs, cytokine and glycoproteins, including SOX2, TOP2A, SPP1, COL1A1, and TIMP1 as potential drivers of lung cancer.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 39888730
BACKGROUND: Lung cancer is a primary global health concern, responsible for a considerable portion of cancer-related fatalities worldwide. Understanding its molecular complexities is crucial for identifying potential targets for treatment. The goal i...
Biomarkers, Tumor Collagen Type I Collagen Type I, alpha 1 Chain DNA Topoisomerases, Type II Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks Humans Lung Neoplasms Machine Learning Osteopontin Poly-ADP-Ribose Binding Proteins Protein Interaction Maps SOXB1 Transcription Factors Tissue Inhibitor of Metalloproteinase-1
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Identification of novel biomarkers for atherosclerosis using single-cell RNA sequencing and machine learning.

Mammalian genome : official journal of the International Mammalian Genome Society 39400603
Atherosclerosis (AS) is a predominant etiological factor in numerous cardiovascular diseases, with its associated complications such as myocardial infarction and stroke serving as major contributors to worldwide mortality rates. Here, we devised depe...
Animals Atherosclerosis Biomarkers Collagen Type I Collagen Type I, alpha 1 Chain Gene Expression Profiling Gene Regulatory Networks Humans Machine Learning Mice Sequence Analysis, RNA Single-Cell Analysis
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