AIMC Topic: Drug Delivery Systems

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The ameliorating approach of nanorobotics in the novel drug delivery systems: a mechanistic review.

Journal of drug targeting Mar 10, 2021
Nanoscale robotics have the ability that it can productively transform multiple energy sources into motion and strength which reflects an expeditiously appearing and captivating area for research of robotics. In today's plethora, biomedical nanorobot...
Animals Robotics Nanotechnology Humans Drug Delivery Systems
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The capabilities of nanoelectronic 2-D materials for bio-inspired computing and drug delivery indicate their significance in modern drug design.

Life sciences Feb 22, 2021
Remarkable advancements in the computational techniques and nanoelectronics have attracted considerable interests for development of highly-sophisticated materials (Ms) including the theranostics with optimal characteristics and innovative delivery s...
Electronics Nanostructures Drug Delivery Systems Drug Design Biomimetics Humans Artificial Intelligence
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Prioritizing Pain-Associated Targets with Machine Learning.

Biochemistry Feb 19, 2021
While hundreds of genes have been associated with pain, much of the molecular mechanisms of pain remain unknown. As a result, current analgesics are limited to few clinically validated targets. Here, we trained a machine learning (ML) ensemble model ...
Machine Learning Drug Delivery Systems Drug Design Humans Models, Biological Drug Discovery Pain Analgesics
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Efficient Prediction of In Vitro Piroxicam Release and Diffusion From Topical Films Based on Biopolymers Using Deep Learning Models and Generative Adversarial Networks.

Journal of pharmaceutical sciences Feb 3, 2021
The purpose of this study was to simultaneously predict the drug release and skin permeation of Piroxicam (PX) topical films based on Chitosan (CTS), Xanthan gum (XG) and its Carboxymethyl derivatives (CMXs) as matrix systems. These films were prepar...
Drug Delivery Systems Deep Learning Administration, Cutaneous Piroxicam Chitosan
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Smart Materials for Microrobots.

Chemical reviews Feb 1, 2021
Over the past 15 years, the field of microrobotics has exploded with many research groups from around the globe contributing to numerous innovations that have led to exciting new capabilities and important applications, ranging from drug delivery, t...
Robotics Smart Materials Humans Drug Delivery Systems
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Multi-functionalized micro-helical capsule robots with superior loading and releasing capabilities.

Journal of materials chemistry. B Jan 20, 2021
The functionalization of microrobots is essential for realizing their biomedical application in targeted cargo delivery, but the multifunctional integration of microrobots and controllable cargo delivery remains an enormous challenge at present. This...
Drug Liberation Drug Delivery Systems Robotics Humans
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Fighting viruses with materials science: Prospects for antivirus surfaces, drug delivery systems and artificial intelligence.

Dental materials : official publication of the Academy of Dental Materials Jan 10, 2021
OBJECTIVE: Viruses on environmental surfaces, in saliva and other body fluids represent risk of contamination for general population and healthcare professionals. The development of vaccines and medicines is costly and time consuming. Thus, the devel...
Humans Artificial Intelligence COVID-19 Materials Science Drug Delivery Systems Antiviral Agents
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Magnetically actuated intelligent hydrogel-based child-parent microrobots for targeted drug delivery.

Journal of materials chemistry. B Jan 5, 2021
Small intestine-targeted drug delivery by oral administration has aroused the growing interest of researchers. In this work, the child-parent microrobot (CPM) as a vehicle protects the child microrobots (CMs) under a gastric acid environment and rele...
Surface Properties Lab-On-A-Chip Devices Doxorubicin Hydrogels Magnetite Nanoparticles Magnetic Phenomena Cells, Cultured Humans Drug Delivery Systems Child Particle Size Robotics
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Assessing Drug Development Risk Using Big Data and Machine Learning.

Cancer research Dec 22, 2020
Identifying new drug targets and developing safe and effective drugs is both challenging and risky. Furthermore, characterizing drug development risk, the probability that a drug will eventually receive regulatory approval, has been notoriously hard ...
Drug-Related Side Effects and Adverse Reactions Drug Delivery Systems Male Patient Safety Antineoplastic Agents Humans Risk Assessment Female Big Data Neoplasms Machine Learning Drug Development
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Trends in Micro-/Nanorobotics: Materials Development, Actuation, Localization, and System Integration for Biomedical Applications.

Advanced materials (Deerfield Beach, Fla.) Dec 4, 2020
Micro-/nanorobots (m-bots) have attracted significant interest due to their suitability for applications in biomedical engineering and environmental remediation. Particularly, their applications in in vivo diagnosis and intervention have been the foc...
Robotics Nanotechnology Animals Humans Drug Delivery Systems Wound Healing
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