AIMC Topic: Drug Interactions

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Medical Information Extraction in the Age of Deep Learning.

Yearbook of medical informatics
OBJECTIVES: We survey recent developments in medical Information Extraction (IE) as reported in the literature from the past three years. Our focus is on the fundamental methodological paradigm shift from standard Machine Learning (ML) techniques to ...

BIOINTMED: integrated biomedical knowledge base with ontologies and clinical trials.

Medical & biological engineering & computing
Biomedical data are complex and heterogeneous. An ample reliable quantity of data is important for understanding and exploring the domain. The work aims to integrate biomedical data from various heterogeneous sources like dictionaries or corpus and a...

GCN-BMP: Investigating graph representation learning for DDI prediction task.

Methods (San Diego, Calif.)
One drug's pharmacological activity may be changed unexpectedly, owing to the concurrent administration of another drug. It is likely to cause unexpected drug-drug interactions (DDIs). Several machine learning approaches have been proposed to predict...

Predicting drug-drug interactions using multi-modal deep auto-encoders based network embedding and positive-unlabeled learning.

Methods (San Diego, Calif.)
Drug-drug interactions (DDIs) are crucial for public health and patient safety, which has aroused widespread concern in academia and industry. The existing computational DDI prediction methods are mainly divided into four categories: literature extra...

Extracting drug-drug interactions from texts with BioBERT and multiple entity-aware attentions.

Journal of biomedical informatics
Drug-drug interactions (DDIs) extraction is one of the important tasks in the field of biomedical relation extraction, which plays an important role in the field of pharmacovigilance. Previous neural network based models have achieved good performanc...

Drug-drug interaction extraction via hybrid neural networks on biomedical literature.

Journal of biomedical informatics
Adverse events caused by drug-drug interaction (DDI) not only pose a serious threat to health, but also increase additional medical care expenditure. However, despite the emergence of many excellent text mining-based DDI classification methods, achie...

BioConceptVec: Creating and evaluating literature-based biomedical concept embeddings on a large scale.

PLoS computational biology
A massive number of biological entities, such as genes and mutations, are mentioned in the biomedical literature. The capturing of the semantic relatedness of biological entities is vital to many biological applications, such as protein-protein inter...

Predicting Adverse Drug-Drug Interactions with Neural Embedding of Semantic Predications.

AMIA ... Annual Symposium proceedings. AMIA Symposium
The identification of drug-drug interactions (DDIs) is important for patient safety; yet, compared to other pharmacovigilance work, a limited amount of research has been conducted in this space. Recent work has successfully applied a method of derivi...

Prediction of Side Effects Using Comprehensive Similarity Measures.

BioMed research international
Identifying the potential side effects of drugs is crucial in clinical trials in the pharmaceutical industry. The existing side effect prediction methods mainly focus on the chemical and biological properties of drugs. This study proposes a method th...

Old drug repositioning and new drug discovery through similarity learning from drug-target joint feature spaces.

BMC bioinformatics
BACKGROUND: Detection of new drug-target interactions by computational algorithms is of crucial value to both old drug repositioning and new drug discovery. Existing machine-learning methods rely only on experimentally validated drug-target interacti...