AIMC Topic: Environmental Pollutants

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Assessing the association of multi-environmental chemical exposures on metabolic syndrome: A machine learning approach.

Environment international
Metabolic syndrome (MetS) is a major global public health concern due to its rising prevalence and association with increased risks of cardiovascular disease and type 2 diabetes. Emerging evidence suggests that environmental chemical exposures may pl...

Using machine learning to investigate the influence of the prenatal chemical exposome on neurodevelopment of young children.

Neurotoxicology
Research investigating the prenatal chemical exposome and child neurodevelopment has typically focused on a limited number of chemical exposures and controlled for sociodemographic factors and maternal mental health. Emerging machine learning approac...

Prioritization strategies for non-target screening in environmental samples by chromatography - High-resolution mass spectrometry: A tutorial.

Journal of chromatography. A
Non-target screening (NTS) using chromatography coupled to high-resolution mass spectrometry (HRMS), has become fundamental for detecting and prioritizing chemicals of emerging concern (CECs) in complex environmental matrices. The vast number of gene...

Unraveling the complexity of organophosphorus pesticides: Ecological risks, biochemical pathways and the promise of machine learning.

The Science of the total environment
Organophosphorus pesticides (OPPs) are widely used in agriculture but pose significant ecological and human health risks due to their persistence and toxicity in the environment. While microbial degradation offers a promising solution, gaps remain in...

Advancements in small molecule fluorescent probes for the detection of formaldehyde in environmental and food samples: A comprehensive review.

Food chemistry
Formaldehyde (FA), a hazardous substance with carcinogenicity and mutagenicity, necessitates sensitive and accurate detection methods for protecting public health and the environment. While numerous reviews have explored FA fluorescent probes, the cu...

Advancing non-target analysis of emerging environmental contaminants with machine learning: Current status and future implications.

Environment international
Emerging environmental contaminants (EECs) such as pharmaceuticals, pesticides, and industrial chemicals pose significant challenges for detection and identification due to their structural diversity and lack of analytical standards. Traditional targ...

Explainable no-code OECD-compliant machine learning models to predict the mutagenic activity of polycyclic aromatic hydrocarbons and their radical cation metabolites.

The Science of the total environment
Polycyclic aromatic hydrocarbons (PAHs) are persistent pollutants with well-known genotoxic and mutagenic effects, posing risks to ecosystems and human health. Their hydrophobic nature promotes accumulation in soils and aquatic environments, increasi...

Unveiling the effect of urinary xenoestrogens on chronic kidney disease in adults: A machine learning model.

Ecotoxicology and environmental safety
Exposure to three primary xenoestrogens (XEs), including phthalates, parabens, and phenols, has been strongly associated with chronic kidney disease (CKD). An interpretable machine learning (ML) model was developed to predict CKD using data from the ...

The Mechanism of Bisphenol S-Induced Atherosclerosis Elucidated Based on Network Toxicology, Molecular Docking, and Machine Learning.

Journal of applied toxicology : JAT
The increasing prevalence of environmental pollutants has raised public concern about their potential role in diseases such as atherosclerosis (AS). Existing studies suggest that chemicals, including bisphenol S (BPS), may adversely affect cardiovasc...

PBScreen: A server for the high-throughput screening of placental barrier-permeable contaminants based on multifusion deep learning.

Environmental pollution (Barking, Essex : 1987)
Contaminants capable of crossing the placental barrier (PB) adversely affect female reproduction and fetal development. The rapid identification of PB-permeable contaminants is urgently needed due to the inefficiencies of conventional cell-based tran...