To solve the problem of inaccurate prediction caused by the lack of representativeness of samples due to the small sample size of the collected clinical data when using machine learning methods to predict drug concentration in plasma and describe the...
IEEE journal of biomedical and health informatics
Apr 4, 2023
The monitoring of epilepsy patients in non-hospital environment is highly desirable, where ultra-low power wearable seizure detection devices are essential in such a system. The state-of-the-art epileptic seizure detection algorithms targeting such d...
Collaborative efforts between basic scientists, engineers, and clinicians are enabling translational epileptology. In this article, we summarize the recent advances presented at the International Conference for Technology and Analysis of Seizures (IC...
Computer methods and programs in biomedicine
Feb 24, 2023
BACKGROUND AND OBJECTIVE: Epilepsy is a brain disorder consisting of abnormal electrical discharges of neurons resulting in epileptic seizures. The nature and spatial distribution of these electrical signals make epilepsy a field for the analysis of ...
IEEE journal of biomedical and health informatics
Feb 3, 2023
Accurate early prediction of epileptic seizures can provide timely treatment for patients. Previous studies have mainly focused on a single temporal or spatial dimension, making it difficult to take both relationships into account. Therefore, the eff...
Intracranially-recorded interictal high-frequency oscillations (HFOs) have been proposed as a promising spatial biomarker of the epileptogenic zone. However, HFOs can also be recorded in the healthy brain regions, which complicates the interpretation...
The original stereoelectroencephalography frame-based implantation technique has been proven to be safe and effective. But this procedure is complicated and time-consuming. With the development of modern robotic technology, robot-guided intracerebral...
Biomedical ontologies are widely used to harmonize heterogeneous data and integrate large volumes of clinical data from multiple sources. This study analyzed the utility of ontologies beyond their traditional roles, that is, in addressing a challengi...
IEEE journal of biomedical and health informatics
Nov 10, 2022
The present study investigates the effectiveness of a deep learning neural network for non-invasively localizing the seizure onset zone (SOZ) using multi-modal MRI data that are clinically acquired from children with drug-resistant epilepsy. A cortic...
BMC medical informatics and decision making
Nov 9, 2022
BACKGROUND: Epilepsy is the fourth-most common neurological disorder, affecting an estimated 50 million patients globally. Nearly 40% of patients have uncontrolled seizures yet incur 80% of the cost. Anti-epileptic drugs commonly result in resistance...