AIMC Topic: Fatty Acid Synthase, Type I

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Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.

Scientific reports Jul 1, 2025
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...
Humans Machine Learning Biomarkers Female Male Gene Expression Profiling Transcriptome ROC Curve Protein Interaction Maps Cholesterol Osteoarthritis Clusterin Fatty Acid Synthase, Type I Activating Transcription Factor 3
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Integrative analysis of PANoptosis-related genes in diabetic retinopathy: machine learning identification and experimental validation.

Frontiers in immunology Dec 4, 2024
BACKGROUND: Diabetic retinopathy (DR) is a major complication of diabetes, leading to severe vision impairment. Understanding the molecular mechanisms, particularly PANoptosis, underlying DR is crucial for identifying potential biomarkers and therape...
Humans Diabetic Retinopathy Machine Learning Biomarkers ROC Curve RNA-Seq Gene Regulatory Networks Nomograms Human Umbilical Vein Endothelial Cells Random Forest CD4-Positive T-Lymphocytes Gene Expression Regulation Molecular Targeted Therapy Memory T Cells Fatty Acid Synthase, Type I Phospholipid Transfer Proteins Regulated Cell Death
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