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Gene Expression

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Influence of Garlic (Allium sativum) Clove-Based Selenium Nanoparticles on Status of Nutritional, Biochemical, Enzymological, and Gene Expressions in the Freshwater Prawn Macrobrachium rosenbergii (De Man, 1879).

Biological trace element research
Selenium (Se) is one of the essential micronutrients for performing vital body functions. This study aims at examining the influence of dietary supplementation of garlic clove-based green-synthesized selenium nanoparticles (GBGS-SeNPs, 48-87 nm) on c...

A robust prediction model for evaluation of plastic limit based on sieve # 200 passing material using gene expression programming.

PloS one
This study aims to propose a novel and high-accuracy prediction model of plastic limit (PL) based on soil particles passing through sieve # 200 (0.075 mm) using gene expression programming (GEP). PL is used for the classification of fine-grained soil...

Feature Subset Selection with Optimal Adaptive Neuro-Fuzzy Systems for Bioinformatics Gene Expression Classification.

Computational intelligence and neuroscience
Recently, bioinformatics and computational biology-enabled applications such as gene expression analysis, cellular restoration, medical image processing, protein structure examination, and medical data classification utilize fuzzy systems in offering...

Use of SVM-based ensemble feature selection method for gene expression data analysis.

Statistical applications in genetics and molecular biology
Gene selection is one of the key steps for gene expression data analysis. An SVM-based ensemble feature selection method is proposed in this paper. Firstly, the method builds many subsets by using Monte Carlo sampling. Secondly, ranking all the featu...

Assessment of deep learning and transfer learning for cancer prediction based on gene expression data.

BMC bioinformatics
BACKGROUND: Machine learning is now a standard tool for cancer prediction based on gene expression data. However, deep learning is still new for this task, and there is no clear consensus about its performance and utility. Few experimental works have...

Machine learning approach identifies prominent codons from different degenerate groups influencing gene expression in bacteria.

Genes to cells : devoted to molecular & cellular mechanisms
Unequal usage of synonymous codons is known as codon usage bias (CUB), which is generally different between the high-expression genes (HEG) and low-expression genes (LEG) in organisms is not yet adequately reported across different bacteria. In this ...

A survey on gene expression data analysis using deep learning methods for cancer diagnosis.

Progress in biophysics and molecular biology
Gene Expression Data is the biological data to extract meaningful hidden information from the gene dataset. This gene information is used for disease diagnosis especially in cancer treatment based on the variations in gene expression levels. DNA micr...

Improved prediction of gene expression through integrating cell signalling models with machine learning.

BMC bioinformatics
BACKGROUND: A key problem in bioinformatics is that of predicting gene expression levels. There are two broad approaches: use of mechanistic models that aim to directly simulate the underlying biology, and use of machine learning (ML) to empirically ...

dynDeepDRIM: a dynamic deep learning model to infer direct regulatory interactions using time-course single-cell gene expression data.

Briefings in bioinformatics
Time-course single-cell RNA sequencing (scRNA-seq) data have been widely used to explore dynamic changes in gene expression of transcription factors (TFs) and their target genes. This information is useful to reconstruct cell-type-specific gene regul...

DRLM: A Robust Drug Representation Learning Method and its Applications.

IEEE/ACM transactions on computational biology and bioinformatics
Learning representations from data is a fundamental step for machine learning. High-quality and robust drug representations can broaden the understanding of pharmacology, and improve the modeling of multiple drug-related prediction tasks, which furth...