Technology and health care : official journal of the European Society for Engineering and Medicine
Apr 29, 2016
Finding the minimum number of appropriate biomarkers for specific targets such as a lung cancer has been a challenging issue in bioinformatics. We propose a hierarchical two-phase framework for selecting appropriate biomarkers that extracts candidate...
Combinatorial chemistry & high throughput screening
Jan 1, 2016
BACKGROUND: The breast is an important biological system of human with two distinct states, i.e. normal and tumoral. Research on breast cancer could be based on systematic modeling to contrast the system structures of these two states.
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2016
Recently, feature selection and dimensionality reduction have become fundamental tools for many data mining tasks, especially for processing high-dimensional data such as gene expression microarray data. Gene expression microarray data comprises up t...
Journal of computational biology : a journal of computational molecular cell biology
Jan 1, 2015
Liver cancer is one of the leading causes of cancer mortality worldwide. Hepatocellular carcinoma (HCC) is the main type of liver cancer. We applied a machine learning approach with maximum-relevance-minimum-redundancy (mRMR) algorithm followed by in...