AIMC Topic: Genetic Therapy
Clear Filters Showing 11 to 20 of 36 articles
Artificial Intelligence and Computational Biology in Gene Therapy: A Review.
Biochemical genetics
Apr 18, 2024
One of the trending fields in almost all areas of science and technology is artificial intelligence. Computational biology and artificial intelligence can help gene therapy in many steps including: gene identification, gene editing, vector design, de...
Analysis on key parameters in subretinal injection facilitating a predictable and automated robot-assisted treatment in gene therapy.
The international journal of medical robotics + computer assisted surgery : MRCAS
Aug 16, 2023
BACKGROUND: Subretinal injection (SRI) has become an important surgical method for treating vitreoretinal diseases. Nevertheless, the optimisation of bleb formation in SRI, for the attainment of desired therapeutic outcomes, still requires further in...
Artificial Intelligence (AI)-Aided Structure Optimization for Enhanced Gene Delivery: The Effect of the Polymer Component Distribution (PCD).
ACS applied materials & interfaces
Jul 21, 2023
Gene therapy has emerged as a significant advancement in medicine in recent years. However, the development of effective gene delivery vectors, particularly polymer vectors, remains a significant challenge. Limited understanding of the internal struc...
Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning.
Frontiers in immunology
Apr 27, 2021
A key hurdle to making adeno-associated virus (AAV) capsid mediated gene therapy broadly beneficial to all patients is overcoming pre-existing and therapy-induced immune responses to these vectors. Recent advances in high-throughput DNA synthesis, mu...
Machine learning based CRISPR gRNA design for therapeutic exon skipping.
PLoS computational biology
Jan 8, 2021
Restoring gene function by the induced skipping of deleterious exons has been shown to be effective for treating genetic disorders. However, many of the clinically successful therapies for exon skipping are transient oligonucleotide-based treatments ...
Next-generation drug repurposing using human genetics and network biology.
Current opinion in pharmacology
Jan 22, 2020
Drug repurposing has attracted increased attention, especially in the context of drug discovery rates that remain too low despite a recent wave of approvals for biological therapeutics (e.g. gene therapy). These new biological entities-based treatmen...
Improving the Rate of Translation of Tissue Engineering Products.
Advanced healthcare materials
Aug 6, 2019
Over 100 000 research articles and 9000 patents have been published on tissue engineering (TE) in the past 20 years. Yet, very few TE products have made their way to the market during the same period. Experts have proposed a variety of strategies to ...
Low-Invasive Cell Injection based on Rotational Microrobot.
Advanced biosystems
Apr 1, 2019
The advancement of cell injections has created a need for accurate, efficient, and low-invasive injections. However, the conventional approaches to reduce cell damage during penetration, mainly optimization of micropipette tips and vision-based autom...
Back to the future - The integration of big data with machine learning is re-establishing the importance of predictive correlations in ovarian cancer diagnostics and therapeutics.
Gynecologic oncology
Mar 21, 2018
Artificial intelligence, machine learning, and digitalization systems in the cell and gene therapy sector: a guidance document from the ISCT industry committees.
Cytotherapy
Aug 1, 2025
As artificial intelligence (AI), machine learning (ML) and other digital tools gain prominence across industries, their application in cell and gene therapy (CGT) has become a topic of increasing interest. Discussions at recent meetings of the Intern...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32006
- Neural Networks, Computer 30221
- Algorithms 27397
- Deep Learning 26901
- Artificial Intelligence 24835
- Robotics 13387
- Image Processing, Computer-Assisted 9735
- Retrospective Studies 9342
- Magnetic Resonance Imaging 6346
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4865
- Support Vector Machine 4769
- Computational Biology 4332
- Brain 4129
- Computer Simulation 3935
Recent Journals
- Scientific reports 6775
- Sensors (Basel, Switzerland) 4794
- PloS one 4200
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1916
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1172
- Journal of chemical information and modeling 1064
- Nature communications 1044
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 873
- Journal of medical Internet research 861
- Briefings in bioinformatics 853