AIMC Topic: Humans

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Machine learning to predict completion of treatment for pancreatic cancer.

Journal of surgical oncology
BACKGROUND: Chemotherapy enhances survival rates for pancreatic cancer (PC) patients postsurgery, yet less than 60% complete adjuvant therapy, with a smaller fraction undergoing neoadjuvant treatment. Our study aimed to predict which patients would c...

Manipulating and measuring variation in deep neural network (DNN) representations of objects.

Cognition
We explore how DNNs can be used to develop a computational understanding of individual differences in high-level visual cognition given their ability to generate rich meaningful object representations informed by their architecture, experience, and t...

Minds in movement: embodied cognition in the age of artificial intelligence.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
This theme issue brings together researchers from diverse fields to assess the current status and future prospects of embodied cognition in the age of generative artificial intelligence. In this introduction, we first clarify our view of embodiment a...

Active inference goes to school: the importance of active learning in the age of large language models.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Human learning essentially involves embodied interactions with the material world. But our worlds now include increasing numbers of powerful and (apparently) disembodied generative artificial intelligence (AI). In what follows we ask how best to unde...

A novel deep learning identifier for promoters and their strength using heterogeneous features.

Methods (San Diego, Calif.)
Promoters, which are short (50-1500 base-pair) in DNA regions, have emerged to play a critical role in the regulation of gene transcription. Numerous dangerous diseases, likewise cancer, cardiovascular, and inflammatory bowel diseases, are caused by ...

Deciphering 3'UTR Mediated Gene Regulation Using Interpretable Deep Representation Learning.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The 3' untranslated regions (3'UTRs) of messenger RNAs contain many important cis-regulatory elements that are under functional and evolutionary constraints. It is hypothesized that these constraints are similar to grammars and syntaxes in human lang...

Accuracy and consistency of publicly available Large Language Models as clinical decision support tools for the management of colon cancer.

Journal of surgical oncology
BACKGROUND: Large Language Models (LLM; e.g., ChatGPT) may be used to assist clinicians and form the basis of future clinical decision support (CDS) for colon cancer. The objectives of this study were to (1) evaluate the response accuracy of two LLM-...

Machine learning and natural language processing in clinical trial eligibility criteria parsing: a scoping review.

Drug discovery today
Automatic eligibility criteria parsing in clinical trials is crucial for cohort recruitment leading to data validity and trial completion. Recent years have witnessed an explosion of powerful machine learning (ML) and natural language processing (NLP...