AIMC Topic: Indican
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Factors involved in phenoconversion of CYP3A using 4β-hydroxycholesterol in stable kidney transplant recipients.
Pharmacological reports : PR
Dec 15, 2018
BACKGROUND: Phenoconversion is a phenomenon whereby some genotypic extensive metabolizers transiently exhibit drug metabolizing enzyme activity at similar level as that of poor metabolizers. Renal failure is known to decrease CYP3A activity in humans...
Synbiotic meal decreases uremic toxins in hemodialysis individuals: A placebo-controlled trial.
Food research international (Ottawa, Ont.)
Aug 9, 2018
Generation of uremic toxins p-cresylsulfate (p-CS), indoxyl sulfate (IS) and indole 3-acetic acid (IAA) in hemodialysis (HD) individuals may be associated with the gut flora and recognized markers of disease progression. This study investigated the e...
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