BACKGROUND: Congenital heart disease (CHD) affects approximately 1% of newborns and is a leading cause of mortality in early childhood. Despite the importance of early detection, current screening methods, such as pulse oximetry and auscultation, hav...
Deficits in emotional reactivity and regulation assessed in infancy, including high levels of negative emotionality (NE), low positive emotionality (PE) and low soothability, can predict future affective and behavioral disorders. White matter (WM) tr...
BACKGROUND: Retinopathy of prematurity (ROP) is the leading preventable cause of childhood blindness. A timely intravitreal injection of antivascular endothelial growth factor (anti-VEGF) is required to prevent retinal detachment with consequent visi...
BACKGROUND: Estimating time-since-injury of healing fractures is imprecise, encompassing excessively wide timeframes. Most injured children are evaluated at non-children's hospitals, yet pediatric radiologists can disagree with up to one in six skele...
BACKGROUND: Healthcare practitioners require a robust predictive system to accurately diagnose diseases, especially in young children with conditions such as anemia. Delays in diagnosis and treatment can have severe consequences, potentially leading ...
The use of 3D marker-based motion analysis systems is considered the gold standard for tracking limb movements. However, these systems are expensive, limited to laboratory settings, and difficult to apply when studying paediatric populations. Therefo...
International journal of molecular sciences
Apr 18, 2025
Hepatocellular carcinoma (HCC) is a major complication of tyrosinemia type 1 (HT-1), an inborn error of metabolism affecting tyrosine catabolism. The risk of HCC is higher in late diagnoses despite treatment. Alpha-fetoprotein (AFP) is widely used to...
OBJECTIVES: To validate clinical scores [Testicular Workup for Ischemia and Suspected Torsion (TWIST), testicular torsion (TT) score, Artificial Intelligence-based Score (AIS), Boettcher Alert Score (BALS)] when evaluating children under 18 with non-...
BACKGROUND: Rotavirus is the leading cause of severe dehydrating diarrhea in children under 5 years worldwide. Timely diagnosis is critical, but access to confirmatory testing is limited in hospital settings. Machine learning (ML) models have shown p...
Research investigating the prenatal chemical exposome and child neurodevelopment has typically focused on a limited number of chemical exposures and controlled for sociodemographic factors and maternal mental health. Emerging machine learning approac...
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