AIMC Topic: Machine Learning

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A fusion framework of deep learning and machine learning for predicting sgRNA cleavage efficiency.

Computers in biology and medicine
CRISPR/Cas9 system is a powerful tool for genome editing. Numerous studies have shown that sgRNAs can strongly affect the efficiency of editing. However, it is still not clear what rules should be followed for designing sgRNA with high cleavage effic...

An Explainable Artificial Intelligence Software Tool for Weight Management Experts (PRIMO): Mixed Methods Study.

Journal of medical Internet research
BACKGROUND: Predicting the likelihood of success of weight loss interventions using machine learning (ML) models may enhance intervention effectiveness by enabling timely and dynamic modification of intervention components for nonresponders to treatm...

Design and Evaluation of Deep Learning Models for Continuous Acute Pain Detection Based on Phasic Electrodermal Activity.

IEEE journal of biomedical and health informatics
The current method for assessing pain in clinical practice is subjective and relies on self-reported scales. An objective and accurate method of pain assessment is needed for physicians to prescribe the proper medication dosage, which could reduce ad...

Learning-Based Multimodal Information Fusion and Behavior Recognition of Vascular Interventionists' Operating Skills.

IEEE journal of biomedical and health informatics
The operating skills of vascular interventionists have an important impact on the effect of surgery. However, current research on behavior recognition and skills learning of interventionists' operating skills is limited. In this study, an innovative ...

Semantic-Aware Contrastive Learning for Multi-Object Medical Image Segmentation.

IEEE journal of biomedical and health informatics
Medical image segmentation, or computing voxel-wise semantic masks, is a fundamental yet challenging task in medical imaging domain. To increase the ability of encoder-decoder neural networks to perform this task across large clinical cohorts, contra...

dMIL-Transformer: Multiple Instance Learning Via Integrating Morphological and Spatial Information for Lymph Node Metastasis Classification.

IEEE journal of biomedical and health informatics
Automated classification of lymph node metastasis (LNM) plays an important role in the diagnosis and prognosis. However, it is very challenging to achieve satisfactory performance in LNM classification, because both the morphology and spatial distrib...

Multi-Label Local to Global Learning: A Novel Learning Paradigm for Chest X-Ray Abnormality Classification.

IEEE journal of biomedical and health informatics
Deep neural network (DNN) approaches have shown remarkable progress in automatic Chest X-rays classification. However, existing methods use a training scheme that simultaneously trains all abnormalities without considering their learning priority. In...

The Coming of Age of AI/ML in Drug Discovery, Development, Clinical Testing, and Manufacturing: The FDA Perspectives.

Drug design, development and therapy
Artificial intelligence (AI) and machine learning (ML) represent significant advancements in computing, building on technologies that humanity has developed over millions of years-from the abacus to quantum computers. These tools have reached a pivot...

What is the ecotoxicity of a given chemical for a given aquatic species? Predicting interactions between species and chemicals using recommender system techniques.

SAR and QSAR in environmental research
Ecotoxicological safety assessment of chemicals requires toxicity data on multiple species, despite the general desire of minimizing animal testing. Predictive models, specifically machine learning (ML) methods, are one of the tools capable of solvin...

Machine learning and regression analysis for age estimation from the iliac crest based on computed tomographic explorations in an Indian population.

Medicine, science, and the law
Age estimation constitutes an integral parameter of identification. In children, sub-adults, and young adults, accurate age estimation is vital on various aspects of civil, criminal, and immigration law. The iliac crest presents as a suitable age mar...