AIMC Topic: Mammals
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Scalability of Large Neural Network Simulations via Activity Tracking With Time Asynchrony and Procedural Connectivity.
Neural computation
Aug 16, 2022
We present a new algorithm to efficiently simulate random models of large neural networks satisfying the property of time asynchrony. The model parameters (average firing rate, number of neurons, synaptic connection probability, and postsynaptic dura...
DNAcycP: a deep learning tool for DNA cyclizability prediction.
Nucleic acids research
Apr 8, 2022
DNA mechanical properties play a critical role in every aspect of DNA-dependent biological processes. Recently a high throughput assay named loop-seq has been developed to quantify the intrinsic bendability of a massive number of DNA fragments simult...
Deep Residual Neural Networks Resolve Quartet Molecular Phylogenies.
Molecular biology and evolution
May 1, 2020
Phylogenetic inference is of fundamental importance to evolutionary as well as other fields of biology, and molecular sequences have emerged as the primary data for this task. Although many phylogenetic methods have been developed to explicitly take ...
Microsoft makes splash in AI-enabled lab solutions.
Nature biotechnology
Aug 1, 2019
DIRECTION: a machine learning framework for predicting and characterizing DNA methylation and hydroxymethylation in mammalian genomes.
Bioinformatics (Oxford, England)
Oct 1, 2017
MOTIVATION: 5-Methylcytosine and 5-Hydroxymethylcytosine in DNA are major epigenetic modifications known to significantly alter mammalian gene expression. High-throughput assays to detect these modifications are expensive, labor-intensive, unfeasible...
A fuzzy logic controller based approach to model the switching mechanism of the mammalian central carbon metabolic pathway in normal and cancer cells.
Molecular bioSystems
Jul 19, 2016
Dynamics of large nonlinear complex systems, like metabolic networks, depend on several parameters. A metabolic pathway may switch to another pathway in accordance with the current state of parameters in both normal and cancer cells. Here, most of th...
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