Biochimica et biophysica acta. Reviews on cancer
Apr 10, 2021
This review captures some key lessons learned in the course of helping some of America's leading healthcare AI innovators achieve scale and sustained impact in complex research and care delivery ecosystems. AI innovators may find it useful to access ...
There is a growing focus on making clinical trials more inclusive but the design of trial eligibility criteria remains challenging. Here we systematically evaluate the effect of different eligibility criteria on cancer trial populations and outcomes ...
Medical oncology (Northwood, London, England)
Apr 3, 2021
Gliomas are one of the most devastating primary brain tumors which impose significant management challenges to the clinicians. The aggressive behaviour of gliomas is mainly attributed to their rapid proliferation, unravelled genomics and the blood-br...
Positron emission tomography (PET) plays an increasingly important role in research and clinical applications, catalysed by remarkable technical advances and a growing appreciation of the need for reliable, sensitive biomarkers of human function in h...
BACKGROUND: IBM's Watson for Oncology (WFO) is an artificial intelligence tool that trains by acquiring data from the Memorial Sloan Kettering Cancer Center and learns from test cases and experts. This study aimed to analyze the adequacy and effectiv...
For annotation in cancer genomic medicine, oncologists have to refer to various knowledge bases worldwide and retrieve all information (e.g., drugs, clinical trials, and academic papers) related to a gene variant. However, oncologists find it difficu...
BACKGROUND: Identifying variants that drive tumor progression (driver variants) and distinguishing these from variants that are a byproduct of the uncontrolled cell growth in cancer (passenger variants) is a crucial step for understanding tumorigenes...
Whole-slide histology images contain information that is valuable for clinical and basic science investigations of cancer but extracting quantitative measurements from these images is challenging for researchers who are not image analysis specialists...
BACKGROUND: Due to the rarity of primary bone tumors, precise radiologic diagnosis often requires an experienced musculoskeletal radiologist. In order to make the diagnosis more precise and to prevent the overlooking of potentially dangerous conditio...
The successful translation of artificial intelligence (AI) applications into clinical cancer care practice requires guidance by academic cancer researchers and providers who are well poised to step into leadership roles. In this commentary, the autho...
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