AIMC Topic: Microscopy

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Speeding up reconstruction of 3D tomograms in holographic flow cytometry deep learning.

Lab on a chip
Tomographic flow cytometry by digital holography is an emerging imaging modality capable of collecting multiple views of moving and rotating cells with the aim of recovering their refractive index distribution in 3D. Although this modality allows us ...

Examination of blood samples using deep learning and mobile microscopy.

BMC bioinformatics
BACKGROUND: Microscopic examination of human blood samples is an excellent opportunity to assess general health status and diagnose diseases. Conventional blood tests are performed in medical laboratories by specialized professionals and are time and...

Deep Multi-Feature Transfer Network for Fourier Ptychographic Microscopy Imaging Reconstruction.

Sensors (Basel, Switzerland)
Fourier ptychographic microscopy (FPM) is a potential imaging technique, which is used to achieve wide field-of-view (FOV), high-resolution and quantitative phase information. The LED array is used to irradiate the samples from different angles to ob...

Artificial intelligence and deep learning to map immune cell types in inflamed human tissue.

Journal of immunological methods
Biopsies of inflammatory tissue contain a complex network of interacting cells, orchestrating the immune or autoimmune response. While standard histological examination can identify relationships, it is clear that a great amount of data on each slide...

Automated characterisation of microglia in ageing mice using image processing and supervised machine learning algorithms.

Scientific reports
The resident macrophages of the central nervous system, microglia, are becoming increasingly implicated as active participants in neuropathology and ageing. Their diverse and changeable morphology is tightly linked with functions they perform, enabli...

Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy.

Pharmaceutical research
OBJECTIVE: Digital microscopy is used to monitor particulates such as protein aggregates within biopharmaceutical products. The images that result encode a wealth of information that is underutilized in pharmaceutical process monitoring. For example,...

High-accuracy, direct aberration determination using self-attention-armed deep convolutional neural networks.

Journal of microscopy
Optical microscopes have long been essential for many scientific disciplines. However, the resolution and contrast of such microscopic images are dramatically affected by aberrations. In this study, compacted with adaptive optics, we propose a machin...

DeLTA 2.0: A deep learning pipeline for quantifying single-cell spatial and temporal dynamics.

PLoS computational biology
Improvements in microscopy software and hardware have dramatically increased the pace of image acquisition, making analysis a major bottleneck in generating quantitative, single-cell data. Although tools for segmenting and tracking bacteria within ti...

Using deep learning to predict the outcome of live birth from more than 10,000 embryo data.

BMC pregnancy and childbirth
BACKGROUND: Recently, the combination of deep learning and time-lapse imaging provides an objective, standard and scientific solution for embryo selection. However, the reported studies were based on blastocyst formation or clinical pregnancy as the ...

Gender Identification and Classification of Flies Using Machine Learning Techniques.

Computational and mathematical methods in medicine
is an important genetic model organism used extensively in medical and biological studies. About 61% of known human genes have a recognizable match with the genetic code of Drosophila flies, and 50% of fly protein sequences have mammalian analogues....