The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of biopharmaceu...
Motivated by the need of rapid detection of living microalgae cells in ship ballast water, this study is intended to determine the activities of microalgae using stained microscopic images and detect the living cells with image processing algorithms....
Biomedical physics & engineering express
Jan 29, 2025
Medical imaging is pivotal in early disease diagnosis, providing essential insights that enable timely and accurate detection of health anomalies. Traditional imaging techniques, such as Magnetic Resonance Imaging (MRI), Computer Tomography (CT), ult...
The development of deep learning algorithms has transformed medical image analysis, especially in brain tumor recognition. This research introduces a robust automatic microbrain tumor identification method utilizing the VGG16 deep learning model. Mic...
Polysorbate 20 (PS20) is commonly used as an excipient in therapeutic protein formulations. However, over the course of a therapeutic protein product's shelf life, minute amounts of co-purified host-cell lipases may cause slow hydrolysis of PS20, rel...
Here we present a highly customisable image-based fuzzy logic control (FLC) method for pressure-driven droplet microfluidics. The system is designed to position droplets of different sizes in microfluidic chips of varying channel size in the centre o...
Gram staining has been a frequently used staining protocol in microbiology. It is vulnerable to staining artifacts due to, e.g., operator errors and chemical variations. Here, we introduce virtual Gram staining of label-free bacteria using a trained ...
IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Jan 8, 2025
Accurate assessment of spinal cord vasculature is important for the urgent diagnosis of injury and subsequent treatment. Ultrasound localization microscopy (ULM) offers super-resolution imaging of microvasculature by localizing and tracking individua...
International journal of environmental research and public health
Dec 31, 2024
The gold standard diagnosis for malaria is the microscopic visualization of blood smears to identify parasites, although it is an expert-dependent technique and could trigger diagnostic errors. Artificial intelligence (AI) tools based on digital ima...
Food research international (Ottawa, Ont.)
Dec 30, 2024
Diverse species of yeasts are commonly associated with food and food production environments. The contamination of food products by spoilage yeasts poses significant challenges, leading to quality degradation and food loss. Similarly, the introductio...
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