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Investigating the antifungal activity and mechanism of a microbial pesticide Shenqinmycin against Phoma sp.

Pesticide biochemistry and physiology
Tea white scab (TWS) is a major disease affecting tea trees in mid-elevation regions and often occurs during rainy seasons with low temperatures. This disease is caused by the fungal pathogen Phoma sp. TWS can infect young stems, tender leaves, and t...

Effects and inhibition mechanism of phenazine-1-carboxamide on the mycelial morphology and ultrastructure of Rhizoctonia solani.

Pesticide biochemistry and physiology
The purpose of this research was to explore the effect of phenazine-1-carboxamide (PCN) on Rhizoctonia solani and to elucidate its mechanisms of action. The toxicity of PCN to R. solani was measured using a growth rate method. The results indicated t...

Automated Interpretation of Blood Culture Gram Stains by Use of a Deep Convolutional Neural Network.

Journal of clinical microbiology
Microscopic interpretation of stained smears is one of the most operator-dependent and time-intensive activities in the clinical microbiology laboratory. Here, we investigated application of an automated image acquisition and convolutional neural net...

Capabilities of GPT-4o and Gemini 1.5 Pro in Gram stain and bacterial shape identification.

Future microbiology
Assessing the visual accuracy of two large language models (LLMs) in microbial classification. GPT-4o and Gemini 1.5 Pro were evaluated in distinguishing Gram-positive from Gram-negative bacteria and classifying them as cocci or bacilli using 80 Gra...

Improvement of gram staining effect by ethanol pretreatment and quantization of staining image by unsupervised machine learning.

Archives of microbiology
In this study, we propose an Ethanol Pretreatment Gram staining method that significantly enhances the color contrast of the stain, thereby improving the accuracy of judgement, and demonstrated the effectiveness of the modification by eliminating una...

Virtual Gram staining of label-free bacteria using dark-field microscopy and deep learning.

Science advances
Gram staining has been a frequently used staining protocol in microbiology. It is vulnerable to staining artifacts due to, e.g., operator errors and chemical variations. Here, we introduce virtual Gram staining of label-free bacteria using a trained ...