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Models, Neurological

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Pre-training artificial neural networks with spontaneous retinal activity improves motion prediction in natural scenes.

PLoS computational biology
The ability to process visual stimuli rich with motion represents an essential skill for animal survival and is largely already present at the onset of vision. Although the exact mechanisms underlying its maturation remain elusive, spontaneous activi...

High-level visual processing in the lateral geniculate nucleus revealed using goal-driven deep learning.

Journal of neuroscience methods
BACKGROUND: The Lateral Geniculate Nucleus (LGN) is an essential contributor to high-level visual processing despite being an early subcortical area in the visual system. Current LGN computational models focus on its basic properties, with less empha...

Structural network measures reveal the emergence of heavy-tailed degree distributions in lottery ticket multilayer perceptrons.

Neural networks : the official journal of the International Neural Network Society
Artificial neural networks (ANNs) were originally modeled after their biological counterparts, but have since conceptually diverged in many ways. The resulting network architectures are not well understood, and furthermore, we lack the quantitative t...

Predictive reward-prediction errors of climbing fiber inputs integrate modular reinforcement learning with supervised learning.

PLoS computational biology
Although the cerebellum is typically associated with supervised learning algorithms, it also exhibits extensive involvement in reward processing. In this study, we investigated the cerebellum's role in executing reinforcement learning algorithms, wit...

Understanding the Spatio-Temporal Coupling of Spikes and Spindles in Focal Epilepsy Through a Network-Level Computational Model.

International journal of neural systems
The electrophysiological findings have shown that epileptiform spikes triggering sleep spindles within 1[Formula: see text]s across multiple channels are commonly observed during sleep in focal epilepsy (FE). Such spatio-temporal couplings of spikes ...

Interpretable deep learning for deconvolutional analysis of neural signals.

Neuron
The widespread adoption of deep learning to model neural activity often relies on "black-box" approaches that lack an interpretable connection between neural activity and network parameters. Here, we propose using algorithm unrolling, a method for in...

FPGA implementation of a complete digital spiking silicon neuron for circuit design and network approach.

Scientific reports
When attempting to replicate the same biological spiking neuron model actions of the human brain, the spiking neuron model methodology and hardware realization design for the nervous system of the brain are crucial considerations. This work provides ...

Distributed Synaptic Connection Strength Changes Dynamics in a Population Firing Rate Model in Response to Continuous External Stimuli.

Neural computation
Neural network complexity allows for diverse neuronal population dynamics and realizes higherorder brain functions such as cognition and memory. Complexity is enhanced through chemical synapses with exponentially decaying conductance and greater vari...

Elucidating the Theoretical Underpinnings of Surrogate Gradient Learning in Spiking Neural Networks.

Neural computation
Training spiking neural networks to approximate universal functions is essential for studying information processing in the brain and for neuromorphic computing. Yet the binary nature of spikes poses a challenge for direct gradient-based training. Su...

The Leaky Integrate-and-Fire Neuron Is a Change-Point Detector for Compound Poisson Processes.

Neural computation
Animal nervous systems can detect changes in their environments within hundredths of a second. They do so by discerning abrupt shifts in sensory neural activity. Many neuroscience studies have employed change-point detection (CPD) algorithms to estim...