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Models, Neurological

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A computational framework for optimal control of a self-adjustive neural system with activity-dependent and homeostatic plasticity.

NeuroImage
The control of the brain system has received increasing attention in the domain of brain science. Most brain control studies have been conducted to explore the brain network's graph-theoretic properties or to produce the desired state based on neural...

The role of individual neuron ion conductances in the synchronization processes of neuron networks.

Neural networks : the official journal of the International Neural Network Society
The partial phase synchronization (sometimes called cooperation) of neurons is fundamental for the understanding of the complex behavior of the brain. The lack or the excess of synchronization can generate brain disorders like Parkinson's disease and...

A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer's disease.

Scientific reports
Alzheimer's disease (AD) is the most common type of dementia. Its diagnosis and progression detection have been intensively studied. Nevertheless, research studies often have little effect on clinical practice mainly due to the following reasons: (1)...

Sparse deep predictive coding captures contour integration capabilities of the early visual system.

PLoS computational biology
Both neurophysiological and psychophysical experiments have pointed out the crucial role of recurrent and feedback connections to process context-dependent information in the early visual cortex. While numerous models have accounted for feedback effe...

Cognitive and MRI trajectories for prediction of Alzheimer's disease.

Scientific reports
The concept of Mild Cognitive Impairment (MCI) is used to describe the early stages of Alzheimer's disease (AD), and identification and treatment before further decline is an important clinical task. We selected longitudinal data from the ADNI databa...

Human-scale Brain Simulation via Supercomputer: A Case Study on the Cerebellum.

Neuroscience
Performance of supercomputers has been steadily and exponentially increasing for the past 20 years, and is expected to increase further. This unprecedented computational power enables us to build and simulate large-scale neural network models compose...

Synchronization of Nonidentical Neural Networks With Unknown Parameters and Diffusion Effects via Robust Adaptive Control Techniques.

IEEE transactions on cybernetics
This paper considers the self-synchronization and tracking synchronization issues for a class of nonidentically coupled neural networks model with unknown parameters and diffusion effects. Using the special structure of neural networks with global Li...

Construction and Supervised Learning of Long-Term Grey Cognitive Networks.

IEEE transactions on cybernetics
Modeling a real-world system by means of a neural model involves numerous challenges that range from formulating transparent knowledge representations to obtaining reliable simulation errors. However, that knowledge is often difficult to formalize in...

PsychRNN: An Accessible and Flexible Python Package for Training Recurrent Neural Network Models on Cognitive Tasks.

eNeuro
Task-trained artificial recurrent neural networks (RNNs) provide a computational modeling framework of increasing interest and application in computational, systems, and cognitive neuroscience. RNNs can be trained, using deep-learning methods, to per...

Deep learning encodes robust discriminative neuroimaging representations to outperform standard machine learning.

Nature communications
Recent critical commentaries unfavorably compare deep learning (DL) with standard machine learning (SML) approaches for brain imaging data analysis. However, their conclusions are often based on pre-engineered features depriving DL of its main advant...