AIMC Topic: Molecular Sequence Annotation
Clear Filters Showing 111 to 120 of 260 articles
SGFSC: speeding the gene functional similarity calculation based on hash tables.
BMC bioinformatics
Nov 4, 2016
BACKGROUND: In recent years, many measures of gene functional similarity have been proposed and widely used in all kinds of essential research. These methods are mainly divided into two categories: pairwise approaches and group-wise approaches. Howev...
Integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes.
BMC genomics
Oct 18, 2016
BACKGROUND: Alzheimer's disease (AD) is a complex progressive neurodegenerative disorder commonly characterized by short term memory loss. Presently no effective therapeutic treatments exist that can completely cure this disease. The cause of Alzheim...
Detecting Essential Proteins Based on Network Topology, Gene Expression Data, and Gene Ontology Information.
IEEE/ACM transactions on computational biology and bioinformatics
Oct 7, 2016
The identification of essential proteins in protein-protein interaction (PPI) networks is of great significance for understanding cellular processes. With the increasing availability of large-scale PPI data, numerous centrality measures based on netw...
Inferring Unknown Biological Function by Integration of GO Annotations and Gene Expression Data.
IEEE/ACM transactions on computational biology and bioinformatics
Oct 7, 2016
Characterizing genes with semantic information is an important process regarding the description of gene products. In spite that complete genomes of many organisms have been already sequenced, the biological functions of all of their genes are still ...
ASAP: a machine learning framework for local protein properties.
Database : the journal of biological databases and curation
Oct 2, 2016
Determining residue-level protein properties, such as sites of post-translational modifications (PTMs), is vital to understanding protein function. Experimental methods are costly and time-consuming, while traditional rule-based computational methods...
Skeleton Genetics: a comprehensive database for genes and mutations related to genetic skeletal disorders.
Database : the journal of biological databases and curation
Aug 31, 2016
Genetic skeletal disorders (GSD) involving the skeletal system arises through disturbances in the complex processes of skeletal development, growth and homeostasis and remain a diagnostic challenge because of their clinical heterogeneity and genetic ...
TopoICSim: a new semantic similarity measure based on gene ontology.
BMC bioinformatics
Jul 29, 2016
BACKGROUND: The Gene Ontology (GO) is a dynamic, controlled vocabulary that describes the cellular function of genes and proteins according to tree major categories: biological process, molecular function and cellular component. It has become widely ...
FALDO: a semantic standard for describing the location of nucleotide and protein feature annotation.
Journal of biomedical semantics
Jun 13, 2016
BACKGROUND: Nucleotide and protein sequence feature annotations are essential to understand biology on the genomic, transcriptomic, and proteomic level. Using Semantic Web technologies to query biological annotations, there was no standard that descr...
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update.
Nucleic acids research
May 3, 2016
Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gen...
Protein-protein interaction inference based on semantic similarity of Gene Ontology terms.
Journal of theoretical biology
Apr 23, 2016
Identifying protein-protein interactions is important in molecular biology. Experimental methods to this issue have their limitations, and computational approaches have attracted more and more attentions from the biological community. The semantic si...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32021
- Neural Networks, Computer 30231
- Algorithms 27405
- Deep Learning 26912
- Artificial Intelligence 24844
- Robotics 13389
- Image Processing, Computer-Assisted 9738
- Retrospective Studies 9346
- Magnetic Resonance Imaging 6347
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4866
- Support Vector Machine 4771
- Computational Biology 4333
- Brain 4129
- Computer Simulation 3935
Recent Journals
- Scientific reports 6800
- Sensors (Basel, Switzerland) 4794
- PloS one 4210
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1916
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1172
- Journal of chemical information and modeling 1066
- Nature communications 1047
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 874
- Journal of medical Internet research 864
- Briefings in bioinformatics 853