MOTIVATION: Recently, machine learning models have achieved tremendous success in prioritizing candidate genes for genetic diseases. These models are able to accurately quantify the similarity among disease and genes based on the intuition that simil...
SUMMARY: In recent years, SWATH-MS has become the proteomic method of choice for data-independent-acquisition, as it enables high proteome coverage, accuracy and reproducibility. However, data analysis is convoluted and requires prior information and...
MOTIVATION: CRISPR/Cas9 is a revolutionary gene-editing technology that has been widely utilized in biology, biotechnology and medicine. CRISPR/Cas9 editing outcomes depend on local DNA sequences at the target site and are thus predictable. However, ...
MOTIVATION: Automated function prediction (AFP) of proteins is a large-scale multi-label classification problem. Two limitations of most network-based methods for AFP are (i) a single model must be trained for each species and (ii) protein sequence i...
Previous attempts to classify task from eye movement data have relied on model architectures designed to emulate theoretically defined cognitive processes and/or data that have been processed into aggregate (e.g., fixations, saccades) or statistical ...
Within simulations of molecules deposited on a surface we show that neuroevolutionary learning can design particles and time-dependent protocols to promote self-assembly, without input from physical concepts such as thermal equilibrium or mechanical ...
Methods for estimating the quality of 3D models of proteins are vital tools for driving the acceptance and utility of predicted tertiary structures by the wider bioscience community. Here we describe the significant major updates to ModFOLD, which ha...
The Journal of the Acoustical Society of America
Jul 1, 2021
Polyethylene (PE) pipes are widely used in gas distribution. Their joints are prone to various flaws and are the most problematic part of the pipeline, so the infrastructure industry requires an effective inspection technique. Butt-fusion (BF) is the...
European review for medical and pharmacological sciences
Jul 1, 2021
OBJECTIVE: The rapid onset of pediatric sepsis and the short optimal time for resuscitation pose a severe threat to children's health in the ICU. Timely diagnosis and intervention are essential to curing sepsis, but there is a lack of research on the...
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