AIMC Topic: Organs at Risk

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Registration-guided deep learning image segmentation for cone beam CT-based online adaptive radiotherapy.

Medical physics
PURPOSE: Adaptive radiotherapy (ART), especially online ART, effectively accounts for positioning errors and anatomical changes. One key component of online ART process is accurately and efficiently delineating organs at risk (OARs) and targets on on...

Clinical evaluation of a deep learning model for segmentation of target volumes in breast cancer radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE/OBJECTIVE(S): Precise segmentation of clinical target volumes (CTV) in breast cancer is indispensable for state-of-the art radiotherapy. Despite international guidelines, significant intra- and interobserver variability exists, negatively imp...

Artificial Intelligence Radiotherapy Planning: Automatic Segmentation of Human Organs in CT Images Based on a Modified Convolutional Neural Network.

Frontiers in public health
OBJECTIVE: Precise segmentation of human organs and anatomic structures (especially organs at risk, OARs) is the basis and prerequisite for the treatment planning of radiation therapy. In order to ensure rapid and accurate design of radiotherapy trea...

Dose prediction via distance-guided deep learning: Initial development for nasopharyngeal carcinoma radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Geometric information such as distance information is essential for dose calculations in radiotherapy. However, state-of-the-art dose prediction methods use only binary masks without distance information. This study aims to de...

Deep Learning-Based Automatic Assessment of Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma.

International journal of radiation oncology, biology, physics
PURPOSE: Radiation dermatitis (RD) is a common, unpleasant side effect of patients receiving radiation therapy. In clinical practice, the severity of RD is graded manually through visual inspection, which is labor intensive and often leads to large i...

The feasibility study on the generalization of deep learning dose prediction model for volumetric modulated arc therapy of cervical cancer.

Journal of applied clinical medical physics
PURPOSE: To develop a 3D-Unet dose prediction model to predict the three-dimensional dose distribution of volumetric modulated arc therapy (VMAT) for cervical cancer and test the dose prediction performance of the model in endometrial cancer to explo...

Deep learning-based auto segmentation using generative adversarial network on magnetic resonance images obtained for head and neck cancer patients.

Journal of applied clinical medical physics
PURPOSE: Adaptive radiotherapy requires auto-segmentation in patients with head and neck (HN) cancer. In the current study, we propose an auto-segmentation model using a generative adversarial network (GAN) on magnetic resonance (MR) images of HN can...

Evaluating the clinical acceptability of deep learning contours of prostate and organs-at-risk in an automated prostate treatment planning process.

Medical physics
BACKGROUND: Radiation treatment is considered an effective and the most common treatment option for prostate cancer. The treatment planning process requires accurate and precise segmentation of the prostate and organs at risk (OARs), which is laborio...

A hybrid optimization strategy for deliverable intensity-modulated radiotherapy plan generation using deep learning-based dose prediction.

Medical physics
PURPOSE: To propose a clinically feasible automatic planning solution for external beam intensity-modulated radiotherapy, including dose prediction via a deep learning and voxel-based optimization strategy.