AIMC Topic: Pain Threshold

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Neural mechanisms supporting the relationship between dispositional mindfulness and pain.

Pain Dec 1, 2018
Interindividual differences in pain sensitivity vary as a function of interactions between sensory, cognitive-affective, and dispositional factors. Trait mindfulness, characterized as the innate capacity to nonreactively sustain attention to the pres...
Humans Neural Networks, Computer Female Young Adult Adult Male Middle Aged Image Processing, Computer-Assisted Magnetic Resonance Imaging Brain Mapping Oxygen Pain Pain Management Pain Threshold Visual Analog Scale Mindfulness Psychophysics
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Machine-learned analysis of the association of next-generation sequencing-based human TRPV1 and TRPA1 genotypes with the sensitivity to heat stimuli and topically applied capsaicin.

Pain Jul 1, 2018
Heat pain and its modulation by capsaicin varies among subjects in experimental and clinical settings. A plausible cause is a genetic component, of which TRPV1 ion channels, by their response to both heat and capsaicin, are primary candidates. Howeve...
Humans Machine Learning TRPV Cation Channels Genotype Genetic Association Studies Pain High-Throughput Nucleotide Sequencing Hot Temperature Pain Threshold Capsaicin TRPA1 Cation Channel
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Tashinone II A-sulfoacid-natrum elevates the pain threshold through inhibiting nuclear factor kappa B pathway in neuropathic cancer pain.

Indian journal of cancer Dec 1, 2015
OBJECTIVE: The purpose of this study was to evaluate the effects of Tashinone II A-sulfoacid-natrum on the pain threshold and potential molecular mechanism for neuropathic cancer pain.
Animals Male Mice Mice, Inbred BALB C NF-kappa B Sciatic Nerve Sulfuric Acid Esters Neuralgia Pain Threshold Abietanes Cancer Pain
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