To develop a machine learning-enhanced normal tissue complication probability (NTCP) model for predicting late sciatic nerve toxicity (LSNT) in sacrococcygeal chordoma (SC) and locally recurrent rectal cancer (LRRC) patients undergoing carbon-ion rad...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jun 18, 2025
Popliteal sciatic nerve block is a widely used technique for lower limb anesthesia. However, despite ultrasound guidance, the complex anatomical structures of the popliteal fossa can present challenges, potentially leading to complications. To accura...
Neurostimulation and neural recording are crucial to develop neuroprostheses that can restore function to individuals living with disabilities. While neurostimulation has been successfully translated into clinical use for several applications, it rem...
IEEE transactions on bio-medical engineering
Jan 19, 2024
BACKGROUND: Closed-loop functional electrical stimulation can use recorded nerve signals to create implantable systems that make decisions regarding nerve stimulation in real-time. Previous work demonstrated convolutional neural network (CNN) discrim...
OBJECTIVE: To investigate the feasibility of an ultrasound-guided sciatic nerve block by describing the sonoanatomy and comparing the distribution of two volumes of bupivacaine dye solution for nerve staining.
BACKGROUND: It is difficult to create intuitive methods of controlling prosthetic limbs, often resulting in abandonment. Peripheral nerve interfaces can be used to convert motor intent into commands to a prosthesis. The Extraneural Spatiotemporal Com...
International journal of neural systems
Mar 15, 2023
Electrical stimulation of the peripheral nervous system is a promising therapeutic option for several conditions; however, its effects on tissue and the safety of the stimulation remain poorly understood. In order to devise stimulation protocols that...
Objective: To develop a standardized model of stretch−crush sciatic nerve injury in mice, and to compare outcomes of crush and novel stretch−crush injuries using standard manual gait and sensory assays, and compare them to both semi-automated as well...
BACKGROUND: Traditional histopathologic evaluation of peripheral nerve using brightfield microscopy is resource-intensive, necessitating complex sample preparation. Label-free imaging techniques paired with artificial intelligence-based image reconst...
OBJECTIVE: To test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.
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