AIMC Topic: Potassium Channels, Voltage-Gated

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Elucidating the role of KCTD10 in coronary atherosclerosis: Harnessing bioinformatics and machine learning to advance understanding.

Scientific reports Mar 10, 2025
Atherosclerosis (AS) is increasingly recognized as a chronic inflammatory disease that significantly compromises vascular health and serves as a major contributor to cardiovascular diseases. KCTD10, a protein implicated in a variety of biological pro...
Humans Machine Learning Gene Expression Profiling Computational Biology Databases, Genetic Coronary Artery Disease Potassium Channels, Voltage-Gated
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Dendritic computations captured by an effective point neuron model.

Proceedings of the National Academy of Sciences of the United States of America Jul 10, 2019
Complex dendrites in general present formidable challenges to understanding neuronal information processing. To circumvent the difficulty, a prevalent viewpoint simplifies the neuronal morphology as a point representing the soma, and the excitatory a...
Neural Networks, Computer Animals Rats Rats, Sprague-Dawley Neurons Synapses CA1 Region, Hippocampal Potassium Channels, Voltage-Gated Excitatory Postsynaptic Potentials Voltage-Gated Sodium Channels
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Impact of sub and supra-threshold adaptation currents in networks of spiking neurons.

Journal of computational neuroscience Sep 24, 2015
Neuronal adaptation is the intrinsic capacity of the brain to change, by various mechanisms, its dynamical responses as a function of the context. Such a phenomena, widely observed in vivo and in vitro, is known to be crucial in homeostatic regulatio...
Humans Neural Networks, Computer Computer Simulation Animals Models, Neurological Action Potentials Nerve Tissue Proteins Neurons Nonlinear Dynamics Synapses Calcium Channels Cerebral Cortex Nerve Net Adaptation, Physiological Potassium Channels, Voltage-Gated
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