AIMC Topic: Precision Medicine
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Integrating AI/ML Models for Patient Stratification Leveraging Omics Dataset and Clinical Biomarkers from COVID-19 Patients: A Promising Approach to Personalized Medicine.
International journal of molecular sciences
Mar 26, 2023
The COVID-19 pandemic has presented an unprecedented challenge to the healthcare system. Identifying the genomics and clinical biomarkers for effective patient stratification and management is critical to controlling the spread of the disease. Omics ...
Artificial intelligence in cancer immunotherapy: Applications in neoantigen recognition, antibody design and immunotherapy response prediction.
Seminars in cancer biology
Mar 3, 2023
Cancer immunotherapy is a method of controlling and eliminating tumors by reactivating the body's cancer-immunity cycle and restoring its antitumor immune response. The increased availability of data, combined with advancements in high-performance co...
Towards artificial intelligence to multi-omics characterization of tumor heterogeneity in esophageal cancer.
Seminars in cancer biology
Mar 1, 2023
Esophageal cancer is a unique and complex heterogeneous malignancy, with substantial tumor heterogeneity: at the cellular levels, tumors are composed of tumor and stromal cellular components; at the genetic levels, they comprise genetically distinct ...
Predictive Models for Health Deterioration: Understanding Disease Pathways for Personalized Medicine.
Annual review of biomedical engineering
Feb 28, 2023
Artificial intelligence (AI) and machine learning (ML) methods are currently widely employed in medicine and healthcare. A PubMed search returns more than 100,000 articles on these topics published between 2018 and 2022 alone. Notwithstanding several...
Deep learning in digital pathology for personalized treatment plans of cancer patients.
Seminars in diagnostic pathology
Feb 26, 2023
Over the past decade, many new cancer treatments have been developed and made available to patients. However, in most cases, these treatments only benefit a specific subgroup of patients, making the selection of treatment for a specific patient an es...
Artificial intelligence and digital biomarker in precision pathology guiding immune therapy selection and precision oncology.
Cancer reports (Hoboken, N.J.)
Feb 22, 2023
BACKGROUND: The currently available immunotherapies already changed the strategy how many cancers are treated from first to last line. Understanding even the most complex heterogeneity in tumor tissue and mapping the spatial cartography of the tumor ...
Artificial Intelligence in Brain Tumor Imaging: A Step toward Personalized Medicine.
Current oncology (Toronto, Ont.)
Feb 22, 2023
The application of artificial intelligence (AI) is accelerating the paradigm shift towards patient-tailored brain tumor management, achieving optimal onco-functional balance for each individual. AI-based models can positively impact different stages ...
Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology.
Seminars in cancer biology
Feb 19, 2023
Personalized treatment strategies for cancer frequently rely on the detection of genetic alterations which are determined by molecular biology assays. Historically, these processes typically required single-gene sequencing, next-generation sequencing...
Emerging role of artificial intelligence, big data analysis and precision medicine in pediatrics.
Pediatric research
Feb 17, 2023
Artificial Intelligence and Machine Learning Approaches to Facilitate Therapeutic Drug Management and Model-Informed Precision Dosing.
Therapeutic drug monitoring
Feb 3, 2023
BACKGROUND: Therapeutic drug monitoring (TDM) and model-informed precision dosing (MIPD) have greatly benefitted from computational and mathematical advances over the past 60 years. Furthermore, the use of artificial intelligence (AI) and machine lea...
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