In this work we present a framework for robust deep learning-based VMAT forward dose calculations for the 1.5T MR-linac. A convolutional neural network was trained on the dose of individual multi-leaf-collimator VMAT segments and was used to predict ...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Nov 12, 2022
BACKGROUND AND PURPOSE: Deep Learning (DL) technique has shown great potential but still has limited success in online contouring for MR-guided adaptive radiotherapy (MRgART). This study proposed a patient-specific DL auto-segmentation (DLAS) strateg...
PURPOSE: To simultaneously register all the longitudinal images acquired in a radiotherapy course for analyzing patients' anatomy changes for adaptive radiotherapy (ART).
BACKGROUND: Online adaptive radiation therapy (RT) using hybrid magnetic resonance linear accelerators (MR-Linacs) can administer a tailored radiation dose at each treatment fraction. Daily MR imaging followed by organ and target segmentation adjustm...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Nov 1, 2022
BACKGROUND AND PURPOSE: To investigate the performance of head-and-neck (HN) organs-at-risk (OAR) automatic segmentation (AS) using four atlas-based (ABAS) and two deep learning (DL) solutions.
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Oct 21, 2022
Accurate clinical target volume (CTV) delineation is important for head and neck intensity-modulated radiation therapy. However, delineation is time-consuming and susceptible to interobserver variability (IOV). Based on a manual contouring process co...
. Deep learning (DL) models for fluence map prediction (FMP) have great potential to reduce treatment planning time in intensity-modulated radiation therapy (IMRT) by avoiding the lengthy inverse optimization process. This study aims to improve the r...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Oct 19, 2022
PURPOSE: The first aim was to generate and compare synthetic-CT (sCT) images using a conditional generative adversarial network (cGAN) method (Pix2Pix) for MRI-only prostate radiotherapy planning by testing several generators, loss functions, and hyp...
. Computed tomography (CT) to material property conversion dominates proton range uncertainty, impacting the quality of proton treatment planning. Physics-based and machine learning-based methods have been investigated to leverage dual-energy CT (DEC...
BACKGROUND: Recently, patient rotating devices for gantry-free radiotherapy, a new approach to implement external beam radiotherapy, have been introduced. When a patient is rotated in the horizontal position, gravity causes anatomic deformation. For ...