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Radiotherapy Planning, Computer-Assisted

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Machine learning models to predict the delivered positions of Elekta multileaf collimator leaves for volumetric modulated arc therapy.

Journal of applied clinical medical physics
PURPOSE: Accurate positioning of multileaf collimator (MLC) leaves during volumetric modulated arc therapy (VMAT) is essential for accurate treatment delivery. We developed a linear regression, support vector machine, random forest, extreme gradient ...

Machine learning-based detection of aberrant deep learning segmentations of target and organs at risk for prostate radiotherapy using a secondary segmentation algorithm.

Physics in medicine and biology
The output of a deep learning (DL) auto-segmentation application should be reviewed, corrected if needed and approved before being used clinically. This verification procedure is labour-intensive, time-consuming and user-dependent, which potentially ...

Training, validation, and clinical implementation of a deep-learning segmentation model for radiotherapy of loco-regional breast cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
AIM: To train and validate a comprehensive deep-learning (DL) segmentation model for loco-regional breast cancer with the aim of clinical implementation.

Treatment plan prediction for lung IMRT using deep learning based fluence map generation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Recently, it has been shown that automated treatment planning can be executed by direct fluence prediction from patient anatomy using convolutional neural networks. Proof of principle publications utilise a fixed dose prescription and fixed ...

AI-based optimization for US-guided radiation therapy of the prostate.

International journal of computer assisted radiology and surgery
OBJECTIVES: Fast volumetric ultrasound presents an interesting modality for continuous and real-time intra-fractional target tracking in radiation therapy of lesions in the abdomen. However, the placement of the ultrasound probe close to the target s...

Automatic contouring QA method using a deep learning-based autocontouring system.

Journal of applied clinical medical physics
PURPOSE: To determine the most accurate similarity metric when using an independent system to verify automatically generated contours.

Development of an anthropomorphic multimodality pelvic phantom for quantitative evaluation of a deep-learning-based synthetic computed tomography generation technique.

Journal of applied clinical medical physics
PURPOSE: The objective of this study was to fabricate an anthropomorphic multimodality pelvic phantom to evaluate a deep-learning-based synthetic computed tomography (CT) algorithm for magnetic resonance (MR)-only radiotherapy.

Toward automatic beam angle selection for pencil-beam scanning proton liver treatments: A deep learning-based approach.

Medical physics
BACKGROUND: Dose deposition characteristics of proton radiation can be advantageous over photons. Proton treatment planning, however, poses additional challenges for the planners. Proton therapy is usually delivered with only a small number of beam a...

Millisecond speed deep learning based proton dose calculation with Monte Carlo accuracy.

Physics in medicine and biology
Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or Monte Carlo (MC) methods. We present ...

Registration-guided deep learning image segmentation for cone beam CT-based online adaptive radiotherapy.

Medical physics
PURPOSE: Adaptive radiotherapy (ART), especially online ART, effectively accounts for positioning errors and anatomical changes. One key component of online ART process is accurately and efficiently delineating organs at risk (OARs) and targets on on...