AIMC Topic: Radiotherapy Planning, Computer-Assisted

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X-ray dose profiles using artificial neural networks.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
This paper introduces a novel computational method to simulate and predict radiation dose profiles in a water phantom irradiated by X-rays of 6 and 15 MV at different depths and field sizes using Artificial Neural Networks within the error margin req...

Improved accuracy of auto-segmentation of organs at risk in radiotherapy planning for nasopharyngeal carcinoma based on fully convolutional neural network deep learning.

Oral oncology
OBJECTIVE: We examined a modified encoder-decoder architecture-based fully convolutional neural network, OrganNet, for simultaneous auto-segmentation of 24 organs at risk (OARs) in the head and neck, followed by validation tests and evaluation of cli...

Deep learning-based internal gross target volume definition in 4D CT images of lung cancer patients.

Medical physics
BACKGROUND: Contouring of internal gross target volume (iGTV) is an essential part of treatment planning in radiotherapy to mitigate the impact of intra-fractional target motion. However, it is usually time-consuming and easily subjected to intra-obs...

Deep Learning-based Non-rigid Image Registration for High-dose Rate Brachytherapy in Inter-fraction Cervical Cancer.

Journal of digital imaging
In this study, an inter-fraction organ deformation simulation framework for the locally advanced cervical cancer (LACC), which considers the anatomical flexibility, rigidity, and motion within an image deformation, was proposed. Data included 57 CT s...

Robust deep learning-based forward dose calculations for VMAT on the 1.5T MR-linac.

Physics in medicine and biology
In this work we present a framework for robust deep learning-based VMAT forward dose calculations for the 1.5T MR-linac. A convolutional neural network was trained on the dose of individual multi-leaf-collimator VMAT segments and was used to predict ...

Patient-specific daily updated deep learning auto-segmentation for MRI-guided adaptive radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Deep Learning (DL) technique has shown great potential but still has limited success in online contouring for MR-guided adaptive radiotherapy (MRgART). This study proposed a patient-specific DL auto-segmentation (DLAS) strateg...

Seq2Morph: A deep learning deformable image registration algorithm for longitudinal imaging studies and adaptive radiotherapy.

Medical physics
PURPOSE: To simultaneously register all the longitudinal images acquired in a radiotherapy course for analyzing patients' anatomy changes for adaptive radiotherapy (ART).

Patient-specific transfer learning for auto-segmentation in adaptive 0.35 T MRgRT of prostate cancer: a bi-centric evaluation.

Medical physics
BACKGROUND: Online adaptive radiation therapy (RT) using hybrid magnetic resonance linear accelerators (MR-Linacs) can administer a tailored radiation dose at each treatment fraction. Daily MR imaging followed by organ and target segmentation adjustm...

Comparison of atlas-based and deep learning methods for organs at risk delineation on head-and-neck CT images using an automated treatment planning system.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: To investigate the performance of head-and-neck (HN) organs-at-risk (OAR) automatic segmentation (AS) using four atlas-based (ABAS) and two deep learning (DL) solutions.

Clinical target volume segmentation based on gross tumor volume using deep learning for head and neck cancer treatment.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Accurate clinical target volume (CTV) delineation is important for head and neck intensity-modulated radiation therapy. However, delineation is time-consuming and susceptible to interobserver variability (IOV). Based on a manual contouring process co...