AIMC Topic: RNA Polymerase II

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Identification of the human DPR core promoter element using machine learning.

Nature Sep 9, 2020
The RNA polymerase II (Pol II) core promoter is the strategic site of convergence of the signals that lead to the initiation of DNA transcription, but the downstream core promoter in humans has been difficult to understand. Here we analyse the human ...
Consensus Sequence TATA Box RNA Polymerase II Mutagenesis Cells Transcription, Genetic Base Sequence Promoter Regions, Genetic Gene Expression Regulation High-Throughput Nucleotide Sequencing Support Vector Machine Datasets as Topic HeLa Cells Computer Simulation Models, Genetic Humans
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Species composition of and fumonisin production by the Fusarium fujikuroi species complex isolated from Korean cereals.

International journal of food microbiology Dec 13, 2017
To assess the risk of fumonisin contamination in Korean cereals, we isolated colonies of the Fusarium fujikuroi species complex (FFSC) from barley, maize, rice and soybean samples from 2011 to 2015. A total of 878 FFSC strains were isolated mostly fr...
RNA Polymerase II Fusarium Peptide Elongation Factor 1 Fumonisins Phylogeny Biodiversity Edible Grain
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A machine learning-based framework for modeling transcription elongation.

Proceedings of the National Academy of Sciences of the United States of America Feb 9, 2021
RNA polymerase II (Pol II) generally pauses at certain positions along gene bodies, thereby interrupting the transcription elongation process, which is often coupled with various important biological functions, such as precursor mRNA splicing and gen...
Epigenesis, Genetic DNA Methylation Machine Learning Humans Binding Sites RNA Polymerase II Histones RNA Splice Sites Transcription Elongation, Genetic RNA Splicing Nucleotide Motifs HEK293 Cells Genome, Human Base Sequence Models, Biological HeLa Cells Protein Processing, Post-Translational
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TSSPlant: a new tool for prediction of plant Pol II promoters.

Nucleic acids research May 5, 2017
Our current knowledge of eukaryotic promoters indicates their complex architecture that is often composed of numerous functional motifs. Most of known promoters include multiple and in some cases mutually exclusive transcription start sites (TSSs). M...
Genome, Plant Transcription Initiation Site Arabidopsis Promoter Regions, Genetic RNA Polymerase II Neural Networks, Computer Plant Proteins Software Gene Expression Sequence Analysis, DNA Oryza
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