The prerequisite of therapeutic drug design and discovery is to identify novel molecules and developing lead candidates with desired biophysical and biochemical properties. Deep generative models have demonstrated their ability to find such molecules...
An early-warning model to predict in-hospital mortality on admission of COVID-19 patients at an emergency department (ED) was developed and validated using a machine-learning model. In total, 2782 patients were enrolled between March 2020 and Decembe...
International journal of environmental research and public health
Oct 17, 2021
Various intelligent technologies have been applied during COVID-19, which has become a worldwide public health emergency and brought significant challenges to the medical systems around the world. Notably, the application of robots has played a role ...
The increasingly ageing population and the tendency to live alone have led science and engineering researchers to search for health care solutions. In the COVID 19 pandemic, the elderly have been seriously affected in addition to suffering from isola...
The COVID-19 pandemic has affected almost every country causing devastating economic and social disruption and stretching healthcare systems to the limit. Furthermore, while being the current gold standard, existing test methods including NAAT (Nucle...
International journal of environmental research and public health
Oct 14, 2021
The use of mobile fitness apps has been on the rise for the last decade and especially during the worldwide SARS-CoV-2 pandemic, which led to the closure of gyms and to reduced outdoor mobility. Fitness apps constitute a promising means for promoting...
The use of robotics is becoming widespread in healthcare. However, little is known about how robotics can affect the relationship with patients during an emergency or how it impacts clinicians in their organization and work. As a hospital responding ...
The pandemic of COVID-19 is continuing to wreak havoc in 2021, with at least 170 million victims around the world. Healthcare systems are overwhelmed by the large-scale virus infection. Luckily, Internet of Things (IoT) is one of the most effective p...
Computational and mathematical methods in medicine
Oct 13, 2021
COVID-19 has swept through the world since December 2019 and caused a large number of patients and deaths. Spatial prediction on the spread of the epidemic is greatly important for disease control and management. In this study, we predicted the cumul...
Blocking the main replicating enzyme, 3 Chymotrypsin-like protease (3CL) is the most promising drug development strategy against the SARS-CoV-2 virus, responsible for the current COVID-19 pandemic. In the present work, 9101 drugs obtained from the dr...