AIMC Topic: Secretory Pathway

Clear Filters Showing 1 to 3 of 3 articles

Machine learning-based investigation of the cancer protein secretory pathway.

PLoS computational biology Apr 5, 2021
Deregulation of the protein secretory pathway (PSP) is linked to many hallmarks of cancer, such as promoting tissue invasion and modulating cell-cell signaling. The collection of secreted proteins processed by the PSP, known as the secretome, is ofte...
Humans Machine Learning Algorithms Biomarkers, Tumor Neoplasms Cell Line, Tumor Neoplasm Proteins Mutation Cell Transformation, Neoplastic Genes, p53 Secretory Pathway
View on PubMed DOI

Machine Learning of Protein Interactions in Fungal Secretory Pathways.

PloS one Jul 21, 2016
In this paper we apply machine learning methods for predicting protein interactions in fungal secretion pathways. We assume an inter-species transfer setting, where training data is obtained from a single species and the objective is to predict prote...
Machine Learning Algorithms ROC Curve Protein Interaction Maps Evolution, Molecular Databases, Protein Amino Acid Sequence Fungal Proteins Saccharomyces cerevisiae Trichoderma Protein Interaction Mapping Genome, Fungal Secretory Pathway
View on PubMed DOI

A reference library for assigning protein subcellular localizations by image-based machine learning.

The Journal of cell biology Mar 2, 2020
Confocal micrographs of EGFP fusion proteins localized at key cell organelles in murine and human cells were acquired for use as subcellular localization landmarks. For each of the respective 789,011 and 523,319 optically validated cell images, morph...
Humans Machine Learning Animals Image Processing, Computer-Assisted Mice Microscopy, Confocal Cell Line Epithelial Cells Mutation Pattern Recognition, Automated Reference Standards Protein Transport Green Fluorescent Proteins Recombinant Fusion Proteins Secretory Pathway Organelles
View on PubMed DOI
Popular Topics
Recent Journals