AIMC Topic: Sequestosome-1 Protein
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Autophagy-related gene SQSTM1 predicts the prognosis of hepatocellular carcinoma.
Computers in biology and medicine
Jun 1, 2025
BACKGROUND: The relationship between autophagy and the progression of hepatocellular carcinoma (HCC) is notably substantial, yet the underlying mechanisms remain incompletely elucidated. Our objective is to construct a predictive model, thereby provi...
A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro.
Toxicological sciences : an official journal of the Society of Toxicology
May 1, 2019
The failure to predict kidney toxicity of new chemical entities early in the development process before they reach humans remains a critical issue. Here, we used primary human kidney cells and applied a systems biology approach that combines multidim...
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