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Spectrophotometry

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A machine learning approach for rapid early detection of Campylobacter spp. using absorbance spectra collected from enrichment cultures.

PloS one
Enumeration of Campylobacter from environmental waters can be difficult due to its low concentrations, which can still pose a significant health risk. Spectrophotometry is an approach commonly used for fast detection of water-borne pollutants in wate...

Non-invasive prediction of maca powder adulteration using a pocket-sized spectrophotometer and machine learning techniques.

Scientific reports
Discriminating different cultivars of maca powder (MP) and detecting their authenticity after adulteration with potent adulterants such as maize and soy flour is a challenge that has not been studied with non-invasive techniques such as near infrared...

Lesion segmentation using 3D scan and deep learning for the evaluation of facial portwine stain birthmarks.

Photodiagnosis and photodynamic therapy
BACKGROUND: Portwine stain (PWS) birthmarks are congenital vascular malformations. The quantification of PWS area is an important step in lesion classification and treatment evaluation.

Rapid simultaneous analysis of anti human immunodeficiency virus drugs in pharmaceutical formulation by smart spectrophotometry based on multivariate calibration and least squares support vector machine methods.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In this study, two chemometrics methods, including partial least squares regression (PLS) and least squares support vector machine (LS-SVM) were applied for the simultaneous determination of zidovudine (ZDV) and lamivudine (LMV) in synthetic mixtures...

Innovative spectrophotometric methods for simultaneous estimation of the novel two-drug combination: Sacubitril/Valsartan through two manipulation approaches and a comparative statistical study.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Different innovative spectrophotometric methods were introduced for the first time for simultaneous quantification of sacubitril/valsartan in their binary mixture and in their combined dosage form without prior separation through two manipulation app...

Validated Spectrophotometric and RP-HPLC-DAD Methods for the Determination of Ursodeoxycholic Acid Based on Derivatization with 2-Nitrophenylhydrazine.

Journal of AOAC International
This work describes the development, validation, and application of two simple, accurate, and reliable methods for the determination of ursodeoxycholic acid (UDCA) in bulk powder and in pharmaceutical dosage forms. The carboxylic acid group in UDCA w...

Artificial neural network assisted kinetic spectrophotometric technique for simultaneous determination of paracetamol and p-aminophenol in pharmaceutical samples using localized surface plasmon resonance band of silver nanoparticles.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Spectrophotometric analysis method based on the combination of the principal component analysis (PCA) with the feed-forward neural network (FFNN) and the radial basis function network (RBFN) was proposed for the simultaneous determination of paraceta...

Simultaneous Determination of Estradiol Cypionate and Medroxyprogesterone Acetate Hormones in Injectable Suspension by UV Spectrophotometry Based on Least-Squares Support Vector Machine and Fuzzy Inference System: Comparison with HPLC.

Journal of AOAC International
BACKGROUND: The combination of estradiol cypionate (ECA) and medroxyprogesterone acetate (MPA) is used to prevent pregnancy in women. The analysis of the ECA and MPA combination reveals a challenge due to the strong overlap of the spectra of these co...

Simultaneous Quantitative Analysis of Salmeterol and Fluticasone in Inhalation Spray Using HPLC and a Fast Spectrophotometric Technique Combined with a Time Series Neural Network and Multivariate Calibration Methods.

Journal of AOAC International
BACKGROUND: Chromatographic methods have been used for the simultaneous determination of salmeterol (SMT) and fluticasone (FLU). The methods take a lot of analysis time, need sample pre-treatment and large amounts of solvents, and are costly.

Nature inspired computation and ensemble neural network to build a robust model for spectral data.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
UV spectrophotometry was introduced for simultaneous determination of Itraconazole (ITZ) and Secnidazole (SEZ) in their mixture without any prior separation. In this study, fourteen nature-inspired algorithms combined with partial least squares (PLS)...