Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Dec 20, 2023
Modern cancer diagnostics involves extracting tissue specimens from suspicious areas and conducting histotechnical procedures to prepare a digitized glass slide, called Whole Slide Image (WSI), for further examination. These procedures frequently int...
SIGNIFICANCE: Mueller matrix (MM) microscopy has proven to be a powerful tool for probing microstructural characteristics of biological samples down to subwavelength scale. However, in clinical practice, doctors usually rely on bright-field microscop...
Colorectal cancer is a global public health problem with one of the highest death rates. It is the second most deadly type of cancer and the third most frequently diagnosed in the world. The present study focused on metastatic colorectal cancer (mCRC...
Computer methods and programs in biomedicine
May 30, 2023
BACKGROUND AND OBJECTIVES: Combining knowledge of clinical pathologists and deep learning models is a growing trend in morphological analysis of cells circulating in blood to add objectivity, accuracy, and speed in diagnosing hematological and non-he...
Computer methods and programs in biomedicine
Apr 5, 2023
BACKGROUND AND OBJECTIVE: This paper presents the quantitative comparison of three generative models of digital staining, also known as virtual staining, in H&E modality (i.e., Hematoxylin and Eosin) that are applied to 5 types of breast tissue. More...
Phase contrast microscopy, as a noninvasive imaging technique, has been widely used to monitor the behavior of transparent cells without staining or altering them. Due to the optical principle of the specifically-designed microscope, phase contrast m...
There exists a growing interest from the clinical practice research communities in the development of methods to automate HEp-2 stained cells classification procedure from histopathological images. Challenges faced by these methods include variations...
Programmed death ligand-1 (PD-L1) has been recently adopted for breast cancer as a predictive biomarker for immunotherapies. The cost, time, and variability of PD-L1 quantification by immunohistochemistry (IHC) are a challenge. In contrast, hematoxyl...
Autofluorescence lifetime images reveal unique characteristics of endogenous fluorescence in biological samples. Comprehensive understanding and clinical diagnosis rely on co-registration with the gold standard, histology images, which is extremely c...
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