AIMC Topic: Synthetic Biology

Clear Filters Showing 31 to 40 of 106 articles

Enabling AI in synthetic biology through Construction File specification.

PloS one Nov 13, 2023
The Construction File (CF) specification establishes a standardized interface for molecular biology operations, laying a foundation for automation and enhanced efficiency in experiment design. It is implemented across three distinct software projects...
Computer Simulation Humans Software Artificial Intelligence Synthetic Biology Automation
View on PubMed DOI

Generative Artificial Intelligence GPT-4 Accelerates Knowledge Mining and Machine Learning for Synthetic Biology.

ACS synthetic biology Sep 8, 2023
Knowledge mining from synthetic biology journal articles for machine learning (ML) applications is a labor-intensive process. The development of natural language processing (NLP) tools, such as GPT-4, can accelerate the extraction of published inform...
Humans Artificial Intelligence Yarrowia Metabolic Engineering Synthetic Biology Machine Learning
View on PubMed DOI

Deep Neural Networks for Predicting Single-Cell Responses and Probability Landscapes.

ACS synthetic biology Jul 19, 2023
Engineering biology relies on the accurate prediction of cell responses. However, making these predictions is challenging for a variety of reasons, including the stochasticity of biochemical reactions, variability between cells, and incomplete inform...
Synthetic Biology Machine Learning Probability Neural Networks, Computer Gene Regulatory Networks
View on PubMed DOI

De novo design of protein interactions with learned surface fingerprints.

Nature Apr 26, 2023
Physical interactions between proteins are essential for most biological processes governing life. However, the molecular determinants of such interactions have been challenging to understand, even as genomic, proteomic and structural data increase. ...
Synthetic Biology Binding Sites Proteins Protein Interaction Maps Proteomics Protein Binding Computer Simulation Deep Learning Humans
View on PubMed DOI

Synthetic biology, genetic circuits and machine learning: a new age of cancer therapy.

Molecular oncology Apr 1, 2023
Synthetic biology has made it possible to rewire natural cellular responses to treat disease, notably demonstrated by chimeric antigen receptor (CAR) T cells as cancer immunotherapy. Building on the success of T-cell activation using synthetic recept...
Receptors, Chimeric Antigen Neoplasms Machine Learning Humans Synthetic Biology Immunotherapy, Adoptive Gene Regulatory Networks
View on PubMed DOI

Precision engineering of biological function with large-scale measurements and machine learning.

PloS one Mar 29, 2023
As synthetic biology expands and accelerates into real-world applications, methods for quantitatively and precisely engineering biological function become increasingly relevant. This is particularly true for applications that require programmed sensi...
Synthetic Biology Machine Learning
View on PubMed DOI

Designing artificial synthetic promoters for accurate, smart, and versatile gene expression in plants.

Plant communications Feb 9, 2023
With the development of high-throughput biology techniques and artificial intelligence, it has become increasingly feasible to design and construct artificial biological parts, modules, circuits, and even whole systems. To overcome the limitations of...
Artificial Intelligence Crops, Agricultural Gene Expression Promoter Regions, Genetic Synthetic Biology
View on PubMed DOI

Enabling technology and core theory of synthetic biology.

Science China. Life sciences Feb 6, 2023
Synthetic biology provides a new paradigm for life science research ("build to learn") and opens the future journey of biotechnology ("build to use"). Here, we discuss advances of various principles and technologies in the mainstream of the enabling ...
Gene Editing Synthetic Biology Genome Artificial Intelligence Biotechnology
View on PubMed DOI

Metabolic engineering for sustainability and health.

Trends in biotechnology Jan 10, 2023
Bio-based production of chemicals and materials has attracted much attention due to the urgent need to establish sustainability and enhance human health. Metabolic engineering (ME) allows purposeful modification of cellular metabolic, regulatory, and...
Humans Metabolic Engineering Metabolic Networks and Pathways Synthetic Biology Systems Biology Artificial Intelligence
View on PubMed DOI

Perspectives for self-driving labs in synthetic biology.

Current opinion in biotechnology Jan 3, 2023
Self-driving labs (SDLs) combine fully automated experiments with artificial intelligence (AI) that decides the next set of experiments. Taken to their ultimate expression, SDLs could usher a new paradigm of scientific research, where the world is pr...
Synthetic Biology Humans Artificial Intelligence
View on PubMed DOI
Popular Topics
Recent Journals