AIMC Topic: Tissue Scaffolds
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A practical machine learning approach for predicting the quality of 3D (bio)printed scaffolds.
Biofabrication
Jul 25, 2024
3D (Bio)printing is a highly effective method for fabricating tissue engineering scaffolds, renowned for their exceptional precision and control. Artificial intelligence (AI) has become a crucial technology in this field, capable of learning and repl...
Machine learning to mechanically assess 2D and 3D biomimetic electrospun scaffolds for tissue engineering applications: Between the predictability and the interpretability.
Journal of the mechanical behavior of biomedical materials
Jun 17, 2024
Currently, the use of autografts is the gold standard for the replacement of many damaged biological tissues. However, this practice presents disadvantages that can be mitigated through tissue-engineered implants. The aim of this study is to explore ...
An explainable machine learning-based probabilistic framework for the design of scaffolds in bone tissue engineering.
Biomechanics and modeling in mechanobiology
Feb 28, 2024
Recently, 3D-printed biodegradable scaffolds have shown great potential for bone repair in critical-size fractures. The differentiation of the cells on a scaffold is impacted among other factors by the surface deformation of the scaffold due to mecha...
Effects of various cross-linked collagen scaffolds on wound healing in rats model by deep-learning CNN.
Computer methods in biomechanics and biomedical engineering
Feb 15, 2024
Scar tissue is connective tissue formed on the wound during the wound-healing process. The most significant distinction between scar tissue and normal tissue is the appearance of covalent cross-linking and the amount of collagen fibers in the tissue....
Artificial Intelligence-Based 3D Printing Strategies for Bone Scaffold Fabrication and Its Application in Preclinical and Clinical Investigations.
ACS biomaterials science & engineering
Jan 22, 2024
3D printing has become increasingly popular in the field of bone tissue engineering. However, the mechanical properties, biocompatibility, and porosity of the 3D printed bone scaffolds are major requirements for tissue regeneration and implantation a...
Advances in volumetric bioprinting.
Biofabrication
Nov 28, 2023
The three-dimensional (3D) bioprinting technologies are suitable for biomedical applications owing to their ability to manufacture complex and high-precision tissue constructs. However, the slow printing speed of current layer-by-layer (bio)printing ...
Vascular persistence following precision micropuncture.
Microcirculation (New York, N.Y. : 1994)
Nov 10, 2023
OBJECTIVE: The success of engineered tissues continues to be limited by time to vascularization and perfusion. Recently, we described a simple microsurgical approach, termed micropuncture (MP), which could be used to rapidly vascularize an adjacently...
Multimodal Three-Dimensional Printing for Micro-Modulation of Scaffold Stiffness Through Machine Learning.
Tissue engineering. Part A
Oct 26, 2023
The ability to precisely control a scaffold's microstructure and geometry with light-based three-dimensional (3D) printing has been widely demonstrated. However, the modulation of scaffold's mechanical properties through prescribed printing parameter...
Rapid prediction of lab-grown tissue properties using deep learning.
Physical biology
Oct 19, 2023
The interactions between cells and the extracellular matrix are vital for the self-organisation of tissues. In this paper we present proof-of-concept to use machine learning tools to predict the role of this mechanobiology in the self-organisation of...
Automatic Photo-Cross-Linking System for Robotic-Based In Situ Bioprinting.
ACS biomaterials science & engineering
Oct 12, 2023
This work reports the design and validation of an innovative automatic photo-cross-linking device for robotic-based in situ bioprinting. Photo-cross-linking is the most promising polymerization technique when considering biomaterial deposition direct...
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