AIMC Topic: Vaccine Development

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The Role of Artificial Intelligence in Accelerating Vaccine Development: Challenges and Opportunities in Pandemic Preparedness.

The International journal of health planning and management
Artificial intelligence (AI) has been studied and applied to medicines and vaccine development. However, there is still a need to understand the processes used and improve them. With this letter, we draw attention to AI use as a tool in vaccine produ...

Vaccine development using artificial intelligence and machine learning: A review.

International journal of biological macromolecules
The COVID-19 pandemic has underscored the critical importance of effective vaccines, yet their development is a challenging and demanding process. It requires identifying antigens that elicit protective immunity, selecting adjuvants that enhance immu...

Revolutionizing adjuvant development: harnessing AI for next-generation cancer vaccines.

Frontiers in immunology
With the COVID-19 pandemic, the importance of vaccines has been widely recognized and has led to increased research and development efforts. Vaccines also play a crucial role in cancer treatment by activating the immune system to target and destroy c...

Mass Spectrometric and Artificial Intelligence-Based Identification of the Secretome of Plasmodium falciparum Merozoites to Provide Novel Candidates for Vaccine Development Pipeline.

Proteomics. Clinical applications
PURPOSE: Merozoites are the only extracellular form of blood stage parasites, making it a worthwhile target. Multiple invasins that are stored in the merozoite apical organelles, are secreted just prior to invasion, and mediates its interaction with ...

Leveraging artificial intelligence in vaccine development: A narrative review.

Journal of microbiological methods
Vaccine development stands as a cornerstone of public health efforts, pivotal in curbing infectious diseases and reducing global morbidity and mortality. However, traditional vaccine development methods are often time-consuming, costly, and inefficie...

Vaccine design and development: Exploring the interface with computational biology and AI.

International reviews of immunology
Computational biology involves applying computer science and informatics techniques in biology to understand complex biological data. It allows us to collect, connect, and analyze biological data at a large scale and build predictive models. In the t...

Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction.

Scientific reports
Tuberculosis (TB) a disease caused by Mycobacterium tuberculosis (Mtb) poses a significant threat to human life, and current BCG vaccinations only provide sporadic protection, therefore there is a need for developing efficient vaccines. Numerous immu...

Scoping Review of Deep Learning Techniques for Diagnosis, Drug Discovery, and Vaccine Development in Leishmaniasis.

Transboundary and emerging diseases
, a single-cell parasite prevalent in tropical and subtropical regions worldwide, can cause varying degrees of leishmaniasis, ranging from self-limiting skin lesions to potentially fatal visceral complications. As such, the parasite has been the subj...

Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms.

Frontiers in immunology
RNA vaccines represent a milestone in the history of vaccinology. They provide several advantages over more traditional approaches to vaccine development, showing strong immunogenicity and an overall favorable safety profile. While preclinical testin...