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Viruses

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Could chatbots help devise the next pandemic virus?

Science (New York, N.Y.)
An MIT class exercise suggests AI tools can be used to order a bioweapon, but some are skeptical.

Review and perspective on bioinformatics tools using machine learning and deep learning for predicting antiviral peptides.

Molecular diversity
Viruses constitute a constant threat to global health and have caused millions of human and animal deaths throughout human history. Despite advances in the discovery of antiviral compounds that help fight these pathogens, finding a solution to this p...

Sensitivity Evaluation of Enveloped and Non-enveloped Viruses to Ethanol Using Machine Learning: A Systematic Review.

Food and environmental virology
Viral diseases are a severe public health issue worldwide. During the coronavirus pandemic, the use of alcohol-based sanitizers was recommended by WHO. Enveloped viruses are sensitive to ethanol, whereas non-enveloped viruses are considerably less se...

HostNet: improved sequence representation in deep neural networks for virus-host prediction.

BMC bioinformatics
BACKGROUND: The escalation of viruses over the past decade has highlighted the need to determine their respective hosts, particularly for emerging ones that pose a potential menace to the welfare of both human and animal life. Yet, the traditional me...

IPEV: identification of prokaryotic and eukaryotic virus-derived sequences in virome using deep learning.

GigaScience
BACKGROUND: The virome obtained through virus-like particle enrichment contains a mixture of prokaryotic and eukaryotic virus-derived fragments. Accurate identification and classification of these elements are crucial to understanding their roles and...

ViralZone 2024 provides higher-resolution images and advanced virus-specific resources.

Nucleic acids research
ViralZone (http://viralzone.expasy.org) is a knowledge repository for viruses that links biological knowledge and databases. It contains data on virion structure, genome, proteome, replication cycle and host-virus interactions. The new update provide...

Deep Learning and Likelihood Approaches for Viral Phylogeography Converge on the Same Answers Whether the Inference Model Is Right or Wrong.

Systematic biology
Analysis of phylogenetic trees has become an essential tool in epidemiology. Likelihood-based methods fit models to phylogenies to draw inferences about the phylodynamics and history of viral transmission. However, these methods are often computation...

Significance of Artificial Intelligence in the Study of Virus-Host Cell Interactions.

Biomolecules
A highly critical event in a virus's life cycle is successfully entering a given host. This process begins when a viral glycoprotein interacts with a target cell receptor, which provides the molecular basis for target virus-host cell interactions for...