AIMC Journal:
International journal of molecular sciences

Showing 211 to 220 of 423 articles

DeepsmirUD: Prediction of Regulatory Effects on microRNA Expression Mediated by Small Molecules Using Deep Learning.

International journal of molecular sciences Jan 18, 2023
Aberrant miRNA expression has been associated with a large number of human diseases. Therefore, targeting miRNAs to regulate their expression levels has become an important therapy against diseases that stem from the dysfunction of pathways regulated...
Neoplasms Deep Learning Humans MicroRNAs Gene Regulatory Networks Computational Biology
View on PubMed DOI

Recent Studies of Artificial Intelligence on In Silico Drug Distribution Prediction.

International journal of molecular sciences Jan 17, 2023
Drug distribution is an important process in pharmacokinetics because it has the potential to influence both the amount of medicine reaching the active sites and the effectiveness as well as safety of the drug. The main causes of 90% of drug failures...
Artificial Intelligence Drug Design Drug Discovery
View on PubMed DOI

Neural Networks in the Design of Molecules with Affinity to Selected Protein Domains.

International journal of molecular sciences Jan 16, 2023
Drug design with machine learning support can speed up new drug discoveries. While current databases of known compounds are smaller in magnitude (approximately 108), the number of small drug-like molecules is estimated to be between 1023 and 1060. Th...
Molecular Docking Simulation Drug Design Bayes Theorem Protein Domains Neural Networks, Computer Artificial Intelligence
View on PubMed DOI

Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T and T Relaxation Times with Application to Cancer Cell Culture.

International journal of molecular sciences Jan 13, 2023
Artificial intelligence has been entering medical research. Today, manufacturers of diagnostic instruments are including algorithms based on neural networks. Neural networks are quickly entering all branches of medical research and beyond. Analyzing ...
Artificial Intelligence Algorithms Humans Neural Networks, Computer Magnetic Resonance Imaging Cell Culture Techniques Neoplasms Image Processing, Computer-Assisted
View on PubMed DOI

Effectiveness of Semi-Supervised Active Learning in Automated Wound Image Segmentation.

International journal of molecular sciences Dec 31, 2022
Appropriate wound management shortens the healing times and reduces the management costs, benefiting the patient in physical terms and potentially reducing the healthcare system's economic burden. Among the instrumental measurement methods, the image...
Ulcer Humans Image Processing, Computer-Assisted Neural Networks, Computer Supervised Machine Learning
View on PubMed DOI

Deep Learning-Based Artificial Intelligence to Investigate Targeted Nanoparticles' Uptake in TNBC Cells.

International journal of molecular sciences Dec 16, 2022
Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer in women. It has the poorest prognosis along with limited therapeutic options. Smart nano-based carriers are emerging as promising approaches in treating TNBC due to...
Humans Antineoplastic Agents Deep Learning Artificial Intelligence Female Nanoparticles Triple Negative Breast Neoplasms
View on PubMed DOI

Hepatoprotective Activity of Lignin-Derived Polyphenols Dereplicated Using High-Resolution Mass Spectrometry, In Vivo Experiments, and Deep Learning.

International journal of molecular sciences Dec 16, 2022
Chronic liver diseases affect more than 1 billion people worldwide and represent one of the main public health issues. Nonalcoholic fatty liver disease (NAFLD) accounts for the majority of mortal cases, while there is no currently approved therapeuti...
Deep Learning Proteomics Mass Spectrometry Polyphenols Humans Molecular Docking Simulation Non-alcoholic Fatty Liver Disease Lignin
View on PubMed DOI

Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter.

International journal of molecular sciences Dec 16, 2022
Through a combination of comparative modeling, site-directed and classical random mutagenesis approaches, we previously identified critical residues for binding, recognition, and translocation of urea, and its inhibition by 2-thiourea and acetamide i...
Urea Transporters Acetamides Artificial Intelligence Urea Thiourea Molecular Docking Simulation Furylfuramide
View on PubMed DOI

Predicting N6-Methyladenosine Sites in Multiple Tissues of Mammals through Ensemble Deep Learning.

International journal of molecular sciences Dec 7, 2022
N6-methyladenosine (mA) is the most abundant within eukaryotic messenger RNA modification, which plays an essential regulatory role in the control of cellular functions and gene expression. However, it remains an outstanding challenge to detect mRNA ...
Adenosine Deep Learning Computational Biology Mammals RNA Reproducibility of Results Animals
View on PubMed DOI

The New Version of the ANDDigest Tool with Improved AI-Based Short Names Recognition.

International journal of molecular sciences Nov 29, 2022
The body of scientific literature continues to grow annually. Over 1.5 million abstracts of biomedical publications were added to the PubMed database in 2021. Therefore, developing cognitive systems that provide a specialized search for information i...
PubMed Databases, Factual Artificial Intelligence Data Mining Proteins
View on PubMed DOI
Popular Topics
Popular Journals