AI Medical Compendium Journal:
Journal of pharmaceutical and biomedical analysis

Showing 41 to 45 of 45 articles

A rapid integrated bioactivity evaluation system based on near-infrared spectroscopy for quality control of Flos Chrysanthemi.

Journal of pharmaceutical and biomedical analysis Sep 5, 2016
For quality control of herbal medicines or functional foods, integral activity evaluation has become more popular in recent studies. The majority of researchers focus on the relationship between chromatography/mass spectroscopy and bioactivity, but t...
Neural Networks, Computer Spectroscopy, Near-Infrared Time Factors Drugs, Chinese Herbal Drug Evaluation, Preclinical Flowers Chrysanthemum
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Exploiting non-linear relationships between retention time and molecular structure of peptides originating from proteomes and comparing three multivariate approaches.

Journal of pharmaceutical and biomedical analysis Jan 27, 2016
Peptides' retention time prediction is gaining increasing popularity in liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomics. This is a promising approach for improving successful proteome mapping, useful both in identification ...
Humans Artificial Intelligence Peptides Proteome Bacillus subtilis Chromatography, Liquid Models, Chemical Bacterial Proteins Tandem Mass Spectrometry HeLa Cells Quantitative Structure-Activity Relationship Protein Conformation
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A simple and sensitive UHPLC-MS/MS method for quantification of buddlejasaponin IV in rat plasma and its application to a pharmacokinetic study.

Journal of pharmaceutical and biomedical analysis Dec 29, 2015
Buddlejasaponin IV (BS-IV), a natural triterpene saponin isolated from several herbal plants, has drawn a lot of attention for its anti-inflammatory, antinociceptive, antihyperlipidemia, and antitumor activities. In this study, a simple and sensitive...
Animals Male Rats, Wistar Rats Dose-Response Relationship, Drug Triterpenes Chromatography, High Pressure Liquid Tandem Mass Spectrometry Administration, Oral Saponins
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Quantitative analysis of maytansinoid (DM1) in human serum by on-line solid phase extraction coupled with liquid chromatography tandem mass spectrometry - Method validation and its application to clinical samples.

Journal of pharmaceutical and biomedical analysis Dec 22, 2015
A sensitive and specific method was developed and validated for the quantitation of maytansinoid (DM1) in human serum using on-line solid phase extraction (SPE)-liquid chromatography-tandem mass spectrometry (LC-MS/MS). Because DM1 contains a free th...
Humans Reproducibility of Results Neoplasms Chromatography, Liquid Infusions, Intravenous Tandem Mass Spectrometry Solid Phase Extraction Maytansine
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Combination of counterpropagation artificial neural networks and antioxidant activities for comprehensive evaluation of associated-extraction efficiency of various cyclodextrins in the traditional Chinese formula Xue-Zhi-Ning.

Journal of pharmaceutical and biomedical analysis Aug 12, 2015
Xue-Zhi-Ning (XZN) is a widely used traditional Chinese medicine formula to treat hyperlipidemia. Recently, cyclodextrins (CDs) have been extensively used to minimize problems relative to medicine bioavailability, such as low solubility and poor stab...
Neural Networks, Computer Antioxidants Drugs, Chinese Herbal Chromatography, High Pressure Liquid Lipid Peroxidation Biphenyl Compounds Picrates Cyclodextrins Technology, Pharmaceutical Chemistry, Pharmaceutical Hydroxyl Radical
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