AI Medical Compendium Journal:
PLoS computational biology

Showing 51 to 60 of 484 articles

Exploring the potential of structure-based deep learning approaches for T cell receptor design.

PLoS computational biology
Deep learning methods, trained on the increasing set of available protein 3D structures and sequences, have substantially impacted the protein modeling and design field. These advancements have facilitated the creation of novel proteins, or the optim...

Integrating dynamic models and neural networks to discover the mechanism of meteorological factors on Aedes population.

PLoS computational biology
Aedes mosquitoes, known as vectors of mosquito-borne diseases, pose significant risks to public health and safety. Modeling the population dynamics of Aedes mosquitoes requires comprehensive approaches due to the complex interplay between biological ...

HELP: A computational framework for labelling and predicting human common and context-specific essential genes.

PLoS computational biology
Machine learning-based approaches are particularly suitable for identifying essential genes as they allow the generation of predictive models trained on features from multi-source data. Gene essentiality is neither binary nor static but determined by...

Ten quick tips for ensuring machine learning model validity.

PLoS computational biology
Artificial Intelligence (AI) and Machine Learning (ML) models are increasingly deployed on biomedical and health data to shed insights on biological mechanism, predict disease outcomes, and support clinical decision-making. However, ensuring model va...

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks.

PLoS computational biology
Viruses of microbes are ubiquitous biological entities that reprogram their hosts' metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental ...

Comparison and benchmark of deep learning methods for non-coding RNA classification.

PLoS computational biology
The involvement of non-coding RNAs in biological processes and diseases has made the exploration of their functions crucial. Most non-coding RNAs have yet to be studied, creating the need for methods that can rapidly classify large sets of non-coding...

Oscillations in an artificial neural network convert competing inputs into a temporal code.

PLoS computational biology
The field of computer vision has long drawn inspiration from neuroscientific studies of the human and non-human primate visual system. The development of convolutional neural networks (CNNs), for example, was informed by the properties of simple and ...

Cracking the neural code for word recognition in convolutional neural networks.

PLoS computational biology
Learning to read places a strong challenge on the visual system. Years of expertise lead to a remarkable capacity to separate similar letters and encode their relative positions, thus distinguishing words such as FORM and FROM, invariantly over a lar...

A Physics-Informed Neural Network approach for compartmental epidemiological models.

PLoS computational biology
Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns. However, their ca...