Trends in biotechnology
Sep 15, 2022
Artificial intelligence and machine learning (AI-ML) offer vast potential in optimal design, monitoring, and control of biopharmaceutical manufacturing. The driving forces for adoption of AI-ML techniques include the growing global demand for biother...
Trends in biotechnology
Aug 10, 2022
Robotics offers an unprecedented means to support people's daily lives. However, human-robot interactions remain challenging because of the appearance of robots. Kawai et al. propose to overcome this by growing biological skin equivalents on robots. ...
Trends in biotechnology
Mar 10, 2022
Batch effects (BEs) are technical biases that may confound analysis of high-throughput biotechnological data. BEs are complex and effective mitigation is highly context-dependent. In particular, the advent of high-resolution technologies such as sing...
Trends in biotechnology
Mar 8, 2021
Chemical, manufacturing, and control development timelines occupy a significant part of vaccine end-to-end development. In the on-going race for accelerating timelines, in silico process development constitutes a viable strategy that can be achieved ...
Trends in biotechnology
Jan 28, 2020
Based on the development of automatic devices and rapid assay methods, various high-throughput screening (HTS) strategies have been established for improving the performance of industrial microorganisms. We discuss the most significant factors that c...
Trends in biotechnology
Jan 21, 2020
Individualizing patient treatment is a core objective of the medical field. Reaching this objective has been elusive owing to the complex set of factors contributing to both disease and health; many factors, from genes to proteins, remain unknown in ...
Trends in biotechnology
Sep 13, 2019
SpCas9 creates blunt end cuts in the genome and generates random and unpredictable mutations through error-prone repair systems. However, a growing body of recent evidence points instead to Cas9-induced staggered end generation, nonrandomness of muta...
Trends in biotechnology
Aug 28, 2019
Metabolomics is a powerful tool to rationally guide the metabolic engineering of synthetic bioproduction pathways. Current reports indicate great potential to further develop metabolomics-directed synthetic bioproduction. Advanced mass metabolomics m...
Trends in biotechnology
Aug 17, 2019
Controlling the expression of genes is one of the key challenges of synthetic biology. Until recently fine-tuned control has been out of reach, particularly in eukaryotes owing to their complexity of gene regulation. With advances in machine learning...
Trends in biotechnology
Oct 22, 2018
Artificial intelligence (AI) is profoundly changing biotechnological innovation. Beyond direct application, it is also a useful tool for adaptive learning and forging new conceptual connections within the vast network of knowledge for the advancement...