Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid-beta accumulation, neurofibrillary tangl...
Despite the remarkable achievements of deep learning networks in analyzing neuroimaging data for various tasks linked to brain functions and disorders, the opaque nature of these models and their interpretability challenges pose significant barriers ...
Computer methods and programs in biomedicine
Aug 1, 2025
BACKGROUND AND OBJECTIVE: In recent years, the association between metabolites and complex human diseases has increasingly been recognized as a major research focus. Traditional wet-lab experiments are considered time-consuming and labor-intensive, w...
PURPOSE OF REVIEW: This review explores the use of brain age estimation from MRI scans as a biomarker of brain health. With disorders like Alzheimer's and Parkinson's increasing globally, there is an urgent need for early detection tools that can ide...
BACKGROUND: Hippocampal atrophy is a key marker of Alzheimer's disease (AD) and mild cognitive impairment (MCI). Diverse artificial intelligence (AI) architectures for automated hippocampal segmentation have been increasingly reported in neuroimaging...
BACKGROUND AND OBJECTIVES: Distinguishing neurodegenerative diseases is a challenging task requiring neurologic expertise. Clinical decision support systems (CDSSs) powered by machine learning (ML) and artificial intelligence can assist with complex ...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jul 1, 2025
INTRODUCTION: Artificial intelligence (AI) models have been applied to differential dementia detection tasks in brain images from curated, high-quality benchmark databases, but not real-world data in hospitals.
IMPORTANCE: Recent data point to the impact of non-traditional environmental and social factors on Alzheimer's Disease-Related Dementias (ADRD) mortality. Our study aimed to determine the extent to which antecedent air pollution, social vulnerability...
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive cognitive decline, necessitating early diagnosis for effective treatment. This study presents the Relational Bi-level Aggregation Graph Convolutional Network with...
The journals of gerontology. Series B, Psychological sciences and social sciences
Jun 10, 2025
The National Institute on Aging (NIA) is at the forefront of leveraging advances in artificial intelligence (AI) to better understanding of aging and the diagnosis and treatment of Alzheimer's Disease (AD) and Alzheimer's disease-related dementias (A...
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