AIMC Topic: Artesunate

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Artesunate alleviates chronic allergic rhinitis and asthma syndrome via the CCR3/NF-κB pathway: a comprehensive analysis.

International immunopharmacology Sep 18, 2025
BACKGROUND: Chronic allergic rhinitis and asthma syndrome (CARAS) is a comorbid inflammatory condition affecting both upper and lower airways, with limited treatment options. Artesunate (ART), a derivative of artemisinin, has shown anti-inflammatory ...
Humans Cytokines Asthma Animals Male Lung Molecular Docking Simulation Mice Signal Transduction Disease Models, Animal Mice, Inbred BALB C Chronic Disease NF-kappa B Anti-Inflammatory Agents STAT3 Transcription Factor Rhinitis, Allergic Artesunate Receptors, CCR3
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Machine learning analysis plans for randomised controlled trials: detecting treatment effect heterogeneity with strict control of type I error.

Trials Feb 10, 2020
BACKGROUND: Retrospective exploratory analyses of randomised controlled trials (RCTs) seeking to identify treatment effect heterogeneity (TEH) are prone to bias and false positives. Yet the desire to learn all we can from exhaustive data measurements...
Humans Machine Learning Algorithms Retrospective Studies Adult Treatment Outcome Randomized Controlled Trials as Topic Plasmodium falciparum Antimalarials Malaria, Falciparum Asia Artesunate Quinine
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