AIMC Topic: Artificial Intelligence

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Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery.

Biochemical Society transactions
Trypanosomatids are protozoan parasites that cause human and animal neglected diseases. Despite global efforts, effective treatments are still much needed. Phenotypic screens have provided several chemical leads for drug discovery, but the mechanism ...

[Frontiers and development in live-cell super-resolution fluorescence microscopy].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
This paper reviews the research progress on live-cell super-resolution fluorescence microscopy, discusses the current research status and hotspots in this field, and summarizes the technological application of super-resolution fluorescence microscopy...

Solving data quality issues of fundus images in real-world settings by ophthalmic AI.

Cell reports. Medicine
Liu et al. develop a deep-learning-based flow cytometry-like image quality classifier, DeepFundus, for the automated, high-throughput, and multidimensional classification of fundus image quality. DeepFundus significantly improves the real-world perfo...

Code-free machine learning for classification of central nervous system histopathology images.

Journal of neuropathology and experimental neurology
Machine learning (ML), an application of artificial intelligence, is currently transforming the analysis of biomedical data and specifically of biomedical images including histopathology. The promises of this technology contrast, however, with its cu...

Large Language Models and the Reverse Turing Test.

Neural computation
Large language models (LLMs) have been transformative. They are pretrained foundational models that are self-supervised and can be adapted with fine-tuning to a wide range of natural language tasks, each of which previously would have required a sepa...

The Quest for Cognition in Purposive Action: From Cybernetics to Quantum Computing.

Journal of integrative neuroscience
Norbert Wiener and Nikolai Bernstein set the stage for a worldwide multidisciplinary attempt to understand how purposive action is integrated with cognition in a circular, bidirectional manner, both in life sciences and engineering. Such a 'workshop'...

How, for whom, and in what contexts will artificial intelligence be adopted in pathology? A realist interview study.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: There is increasing interest in using artificial intelligence (AI) in pathology to improve accuracy and efficiency. Studies of clinicians' perceptions of AI have found only moderate acceptability, suggesting further research is needed rega...

Using artificial intelligence to improve pain assessment and pain management: a scoping review.

Journal of the American Medical Informatics Association : JAMIA
CONTEXT: Over 20% of US adults report they experience pain on most days or every day. Uncontrolled pain has led to increased healthcare utilization, hospitalization, emergency visits, and financial burden. Recognizing, assessing, understanding, and t...